Omnical, Parvo, Cosmed, and DeltaTrac had greater accuracy and reliability. The small number of instruments tested and expected differences in gas calibration variability limits the generalizability of conclusions. Finally, humidity and temperature could be modified in the laboratory to optimize IC conditions.

Optimizing FANA modified spherical nucleic acids (FANA-SNAs) for highly efficient delivery of nucleic acid therapeutics.

Objective: Holiday weight gain is reported to be 0.4 to 1.5 kg and may contribute to annual weight gain. The objective of this study was to test the efficacy of daily self-weighing (DSW) using visual graphical feedback (GF) to prevent holiday weight gain. Methods: A total of 111 adults were randomly assigned into a control or DSW + GF group and completed the preholiday visit (v1; before Thanksgiving), the postholiday visit (v2; after New Year's Day), and the followup visit (v3; 14 weeks after v2). The participants in the DSW + GF group performed DSW with Wi-Fi scales during the holidays and were told to try not to gain weight above baseline weight.Results: There was no change in weight with DSW + GF, whereas the control group gained weight from v1 to v2 (−0.13 ± 0.27 kg vs. 2.65 ± 0.33 kg, P < 0.001, respectively). In the control group, weight change was similar between individuals with overweight or obesity (OW/OB) versus individuals with normal weight (2.71 ± 0.48 kg vs. 2.62 ± 0.43 kg, not significant, respectively). For DSW + GF, individuals with OW/OB lost weight whereas those with normal weight maintained weight during the holidays (−1.46 ± 0.62 kg vs. 0.33 ± 0.27 kg, P = 0.01, respectively). The control group lost weight during the follow-up (−1.14 ± 0.43 kg, P = 0.01; v2 to v3) but retained 57% of weight gain; therefore, weight gain from v1 to v3 was significant (1.51 ± 0.39 kg, P < 0.001). Conclusions: DSW + GF was a successful approach to prevent holiday weight gain, with those with OW/ OB responding most favorably to DSW + GF.Obesity (2019) 27, 908-916.Research has shown that daily self-weighing (DSW) could play an important role in weight maintenance following weight loss, although this is often done in conjunction with other behavior modifications, making it difficult to attribute success solely to . When investigated as the only weight management intervention, a study in adults with obesity showed that DSW can produce clinically significant weight loss (20). DSW has also been effective in preventing age-related weight gain during the first year of college Additional Supporting Information may be found in the online version of this article.

Dietary fatty acids (FA) act as signaling molecules with diverse effects on physiologic function. The aim of this article is to review and summarize the clinical human studies in the literature on how dietary FA composition in meals and diets affects hunger and satiety signaling in the body. Studies examining FA saturation (monounsaturated (MUFA), saturated or polyunsaturated (PUFA) FAs) or FA chain length from high-fat meals/diets were included. Measures of appetite included visual analog scale (VAS) questionnaires, appetite hormones (Cholecystokinin (CCK), glucagon-like peptide-1 (GLP-1), peptide YY (PYY), gastric insulinotropic polypeptide gastric inhibitory peptide (GIP), ghrelin, leptin, insulin) and/or energy intake (EI) data. VAS measures in 9 out of 13 studies were not influenced by FA saturation. PUFAs, followed by MUFAs, tended to induce the greatest stimulatory effect on GLP-1, GIP and PYY, which was found in 6 out of 11 studies measuring appetite-related hormones. Regarding FA chain length, five of six studies show either no difference or less hunger (VAS) and greater satiety hormone levels (two of six studies) for FAs with longer chain lengths. EI does not seem to be affected by the saturation of FAs while EI was inconclusive for studies comparing FA chain length. Possibly due to the inconsistencies in study design, little agreement is observed between the studies on the impact of FA composition on hormonal and subjective measures of appetite as well as EI. Therefore, more research on the long-term impact of dietary FA composition on appetite control may provide clearer outcomes.

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