Objective: This study aimed to explore the profile of evidence-practice implementation and its associated factors among Indonesian Physiotherapists in Jakarta and the surrounding area, Indonesia. Methods: This study was a cross-sectional design and a proportional sampling technique used to calculate the minimum sample as population representative. Twenty-one public and private hospitals and around 104 full-time registered Physiotherapists participated in this study. The study adopted the instruments which have been established to investigate the attitude of Physiotherapists towards Evidence-Based Practice which was developed by Jette (2013). Univariate analysis and logistic regression were employed to see if there are significant relationships between the predictors and outcome. Results: The participants in this study were less than 40 years (61.5%). Participants have been recognized as having worked in the field of physiotherapy with a duration of fewer than ten years (43.3%). For educational background, the participants who certified as Bachelor of Applied Science (B.Sc) was 21.2%. The results revealed the association between predictors and  EBP implementation. Physiotherapists who admit that they were doing self-learning in seeking information and other additional more likely to have a positive attitude towards EBP (OR=1.472). Similarly, working in physiotherapy for more than ten years was positively associated with EBP implementation (OR = 1.009). Conclusion: In general, self intention to develop their skill and their knowledge on  EBP and also the duration of working as physiotherapists were contributed to influencing the attitude of physiotherapists toward Evidence-Based Practice. In future studies, the understanding level of EBP terms should be distinguished. Hence, it could differentiate the physiotherapists from the low-level to the high-level according to their understanding of EBP.