AC. A proposed therapeutic algorithm for colorectal cancer prevention, based on endoscopic polypectomies in patients with multiple colonic polyps.

Objectives. The present study has highlighted the number of tumoral protruzive formations found overall, in a sample of a population that is targeted at a hospital for a varied symptomatology study with patients admitted in the hospital, and not on a lot presumed healthy (without clinical symptoms), as in the case of screening. Material and method. The research was conducted as observational longitudinal study, on a 2000 investigations performed on patients hospitalised in the Witting Clinical Hospital between January 2009 and January 2017. Results. A number of patients out of 2000 colonoscopies were found with 594 tumor formations; of these, 148 have been identified (24.9%) cases of colon cancer 446 75%) and formations (of type polypoid. Conclusions. The study was able to identify more parameters with statistical significance, such as the number of colonoscopies which has varied in relation to the sex of the subjects investigated, the age of patients with colorectal cancer on age levels. The study also show that both sexes cancer occurs at a higher age than the occurrence of polyps, which suggests that early detection of polyps and resection can stop their malignization. Distribution of poliypectomies in relation to the type and degree of polyp malignization varied not statistically significant for both unique and multiple polyps, the maximum frequency being recorded at low dysplasia. Note that in the case of singular polyp, frequency of polyps with high-grade dysplasia was double compared to that recorded for multiple polyps (9% vs. 4%).