Objective: To determine the prevalence of hepatitis B and C infection and its risk factors in Mongolians from 10 to 40 years of age. Method: Randomly selected Mongolians underwent phlebotomy and completed a questionnaire about their medical and family history and risk factors. Participants were screened for qHBsAg, anti-HBs, HBeAg, anti-HBe, anti-HBc markers, and Anti-HCV. Results: 6811 people, 2900 (42.7%) males, and 3911 (57.3%) females participated. Most were from Ulaanbaatar (4685, 69%), with the remaining 2126 (31%) from rural areas. Seven percent were HbsAg positive, 4.2% were HCV positive. Of those10-20 years of age, 5.8% (29) had hepatitis B, 6% (17) had hepatitis C. Of those 21 to 40 years of age, 94.2% (469) had hepatitis B, and 94%(268) had hepatitis C. Children whose mother was HBsAg positive were at higher risk of HBsAg positivity (OR 2.152; 95% CI 1.4; 3.2, p < .0001) as well as those with male gender (OR 1.703; 95% CI 1.17;2.46, p < .005), those phlebotomized for lab tests (OR 1.768; 95% CI 1.14; 2.74, p = .011) ,and those immunized against hepatitis B (OR 0.508; 95% CI 0.35; 0.74, p < .0001). HCV infection was associated with history of dental procedures (OR 1.681; 95% CI 1.01; 2.79, p = .045), using glass syringes (OR 2.131; 95% CI 1.54; 2.95, p < .0001), and previously used needles (OR 2.411; 95% CI 1.09;5.29, p = .028). Conclusions: Among the Mongolian population between 10 and 40 years of age, 7.3% were HbsAg positive, 4.2% were Anti-HCV positive. The risk factors were maternal HbsAg positivity, utilization of glass syringes, reusing needles, phlebotomy for laboratory tests, receiving dental treatment, and the absence of hepatitis B immunization.

Objective: Using high-sensitivity test results of CLEIA we aimed to investigate the prevalence of hepatitis B and C virus, and compare levels of AST, ALT, M2BPGI in the Mongolian population in the age between 40-64. Methods: In order to re ect the administrative and geographical features of Mongolia, the sampling was done at three levels: urban, province center, and rural. Immunological test was measured by chemiluminescence enzyme immunoassay (CLEIA). The statistical package for the social sciences (SPSS) version 25 was used for the statistical analyses. Results: The survey covered 3196 people. 71.8 percent of the patients surveyed had a negative in hepatitis test. 10.1 percent had a positive HBsAg test. 17 percent had a positive anti-HCV test. 1.1 percent had both a positive both HBsAg and anti-HCV (<.0001). AST and ALT increased more frequently during co-infection. M2BPGI protein average level in the non-infected group was 1.00 C.O.I, in the HBsAg positive group 1.65 C.O.I, in the anti-HCV positive group 1.83 C.O.I, and in the co-infection group 1.87 C.O.I (<.0001). Conclusion:10.1 percent of 40-64year-olds in Mongolia were infected with hepatitis B virus, and 17 percent had Hepatitis C virus and 1.1 percent had hepatitis B and C virus co-infections. Serum M2BPGi is increasing in hepatitis C virus infection and in co-infection.

Objectives: Establishment of reference interval for M2BPGI glyco-biomarker in the serum of relatively healthy Mongolian people. Methods: Serum analysis for M2BPGI glyco-biomarker, hepatitis virus markers, and AFP analysis were performed using a fully automated chemiluminescence immunoassay analyzer. Non-parametric methods were used for establishment of reference interval according to the guideline of the Clinical Laboratory Standards Institute. Statistical analysis was done by using SPSS ver. 20.0; SPSS Inc., Chicago, IL software. Results: Total of 3384 people were involved in this study. Of the total participants, 40% were overweight and 31.3% were obese. Also, of the population 10.1 percent were positive for HBsAg, 17 percent were positive for Anti-HCV, and 1.1 percent had co infection of both HBV and HCV. A total of the 316 individuals met the inclusion criteria for reference interval establishment and 77 (24.4%) of them were men and 239 (75.6%) were women. The reference interval of M2BPGI glyco-biomarker for men was 0.883 ± 0.311C.O.I and for women was 0.951 ± 0.411C.O.I. Conclusion: It is determined that the reference interval for M2BPGI glyco-biomarker in the serum of relatively healthy Mongolian people was 0.936 ± 0.391C.O.I.