The review article is devoted to one of the new topical problems in medicine necrosis of the organs of the cranio-maxillofacial region in patients with coronavirus infection, which was first discussed at the end of 2020. Later, doctors of various specialties (otolaryngologists, ophthalmologists, maxillofacial surgeons, neurosurgeons, dentists) from many countries of the world met in their practice with inflammatory-necrotic lesions of the mucous membrane of the nasal cavity and paranasal sinuses, facial skeleton and skull, eyeball, brain. The article highlights the main points of view of scientists about the etiology and pathogenesis of the studied pathology. Summarized data from the largest studies on the epidemiology, risk factors, and symptoms of post-covid necrosis of the cranio-maxillofacial region are presented. The results of various methods for diagnosing this complication multislice computed tomography, magnetic resonance imaging, angiography, are described in detail. Due to the fact that today the role of fungal flora is recognized as the leading one in the etiology of post-covid necrosis of the cranio-maxillofacial region, much attention is paid to cytological, microbiological and pathohistological research methods, which should be aimed at the search for mycelium. The main approaches to the treatment of patients with this pathology are formulated. The article highlights issues important for practical healthcare: interpretation of national clinical guidelines for coronavirus infection in terms of post-covid necrosis of the cranio-maxillofacial region, classification options according to the International Classification of Diseases of the 10th revision, the procedure for providing medical care to this category of patients, the economic consequences of the lack of active prevention methods of the presented complication in patients with COVID-19.

Dentists are always in quest of new methods for the treatment of periodontal diseases, and photodynamic therapy (PDT) is considered one of the most effective methods. A significant improvement in the clinical pic-ture was obtained in all patients throughout the control period of observation of the patients as a result of the treatment with the use of PDT. According to the data from research study it can be said that photodynamic therapy is an effective and gentle method of antibacterial treatment of inflammatory periodontal diseases, which can be effectively used to prevent exacerbations of chronic inflammatory periodontal diseases, to achieve a long-term positive effect and to refuse, in some cases, from surgical methods of treatment. There is a signifi-cant increase in the duration of remission of the disease, improvement of microcirculatory blood circulation in per-iodontal tissues and a small microbial contamination of periodontal pockets of patients treated with photodynam-ic therapy in the long term compared with groups of patients treated with only antiseptic and antibacterial drugs.