A new fossil species of Biomphalaria Preston is described for the Upper Cretaceous of Uruguay (Queguay Formation). The new species is characterized by a conspicuous spiral ornamentation, a unique character within the genus. This new Biomphalaria species is the third known for the Queguay Formation, in addition to B. walteri (Parodiz) and B. reversa Cabrera, Martínez & Norbis. They represent the oldest record of this genus worldwide.
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