Introducción: el tratamiento del cáncer ha evolucionado a pasos acelerados debido a la implementación de las tecnologías de Secuenciación de Nueva Generación (NGS) para la determinación de mutaciones accionables que se pueden beneficiar de terapias dirigidas siendo una opción diferente al manejo médico convencional. En la última década se han establecido en todo el mundo diferentes comités de tumores moleculares (en inglés conocido como Molecular Tumor Board-MTB), con el objetivo de facilitar la interpretación del perfil genómico tumoral y emitir recomendaciones para mejorar las decisiones terapéuticas contra diferentes tipos de cáncer. Sin embargo, esta estrategia ha sido poco explorada en los países en desarrollo, incluyendo Colombia, donde los índices de morbimortalidad del cáncer continúan aumentando anualmente.Objetivos: describir las ventajas y beneficios de implementar un comité de tumores moleculares en Colombia que mejore la práctica de la oncología tradicional. Además, se caracterizó la frecuencia de alteraciones genómicas y las mutaciones accionables en cohorte de pacientes analizados en el MTB
Objective: to identify the demographic, as well as the tobacco and alcohol use characteristics of undergraduate students from a Medellín, Colombia, well-known university during the first 2007 academic period.
Methodology: a transversal descriptive study was carried of a representative population of 1.406 undergraduate students from the said educative institution. The study instrument was an auto-applied questionnaire.
Results: during the study period 1.406 students were interviewed, with an average age of 20,8 years. Other general characteristics of the population were: 51,2% of the interviewed people was female and the predominant marital status was single (97,6%). Annual prevalence of 94,0% and 42,4% for alcohol and tobacco use were found, respectively. Alcoholism risk, according to the CAGE test, was 8%, while nicotine dependence risk was 6% according to the Fagerström test. Males and the 16-24 ages group have the highest substance use prevalence and the highest alcoholismand/or nicotine dependence risk.
Conclusion: alcohol and tobacco use in this studied university is a problem deserving attention from health care offices.
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