This randomized clinical trial investigates noninferiority of fosfomycin vs ceftriaxone or meropenem in achieving clinical and microbiological cure among patients with urinary tract infections due to multidrug-resistant Escherichia coli .

HIV-coinfection is associated with worse response to DAA-based therapy against HCV infection. In patients receiving IFN-free therapy, this fact seems to be mainly driven by a higher rate of relapses among HIV-coinfected subjects.

No abstract

In male HIV patients without diabetes, higher irisin concentrations are positively associated with insulin resistance, NAFLD and subclinical atherosclerosis. However, waist-hip-ratio is the main determinant of insulin resistance, and PAI-1 and lipodystrophy were the strongest determinants of IMT in this population.