BACKGROUNDSkin cancer is the most common malignancy and can be treated in various ways. One
treatment modality is Mohs micrographic surgery. Due to the increasing incidence
of skin cancer in the last decades, there is a need for improvement of the Mohs
technique to optimize its effectiveness. OBJECTIVEThe aim of this study was to evaluate the use of dermoscopy to guide demarcation
of Mohs micrographic surgery margins and ascertain whether this method can reduce
operative time and, therefore, reduce surgical morbidity and cost. METHODS AND MATERIALSThe sample comprised 44 patients who underwent Mohs micrographic surgery,
allocated into two groups: the control group and the intervention group. In the
latter, surgical margins were guided by dermoscopy. RESULTSThere were no statistically significant differences between the two groups by
chi-square analysis (p = 0.399). CONCLUSIONAlthough outcomes were similar in the two groups, demonstrating that dermoscopy
does not help in the demarcation of surgical margins for Mohs micrographic
surgery, the study provides a practical proposal for improvement of the Mohs
technique.
Stiff skin syndrome is a rare cutaneous disease, scleroderma-like disorder that presents in infancy or early childhood with rock-hard skin, limited joint mobility, and mild hypertrichosis. Normally, it occurs in the absence of visceral or muscle involvement. Patients do not present immunologic abnormalities or vascular hyperactivity. We describe two adults who initially were diagnosed suffering from scleroderma but fit criteria for stiff skin syndrome. A review of the clinical range of this disorder and discussion of the differential diagnosis with scleroderma is presented.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.