Optical fibre sensors (OFS), as a result of their unique properties such as small size, no interference with electromagnetic radiation, high sensitivity and the ability to design multiplexed or distributed sensing systems, have found applications ranging from structural health monitoring to biomedical and point of care instrumentation. While the former represents the main commercial application for OFS, there is body of literature concerning the deployment of this versatile sensing platform in healthcare. This paper reviews the different types of OFS and their most recent applications in healthcare. It aims to help clinicians to better understand OFS technology and also provides an overview of the challenges involved in the deployment of developed technology in healthcare. Examples of the application of OFS in healthcare are discussed with particular emphasis on recently (2015–2017) published works to avoid replicating recent review papers. The majority of the work on the development of biomedical OFS stops at the laboratory stage and, with a few exceptions, is not explored in healthcare settings. OFSs have yet to fulfil their great potential in healthcare and methods of increasing the adoption of medical devices based on optical fibres are discussed. It is important to consider these factors early in the device development process for successful translation of the developed sensors to healthcare practice.
The development of reliable, affordable and efficient sensors is a key step in providing tools for efficient monitoring of critical environmental parameters. This review focuses on the use of tapered optical fibres as an environmental sensing platform. Tapered fibres allow access to the evanescent wave of the propagating mode, which can be exploited to facilitate chemical sensing by spectroscopic evaluation of the medium surrounding the optical fibre, by measurement of the refractive index of the medium, or by coupling to other waveguides formed of chemically sensitive materials. In addition, the reduced diameter of the tapered section of the optical fibre can offer benefits when measuring physical parameters such as strain and temperature. A review of the basic sensing platforms implemented using tapered optical fibres and their application for development of fibre-optic physical, chemical and bio-sensors is presented.
A novel approach to chemical application of long period grating (LPG) optical fibers was demonstrated, which were modified with a film nanoassembled by the alternate deposition of SiO(2) nanoparticles (SiO(2) NPs) and poly(diallyldimethyl ammonium chloride) (PDDA). Nanopores of the sensor film could be used for sensitive adsorption of chemical species in water, which induced the changes in the refractive index (RI) of the light propagating in the cladding mode of the optical fiber, with a concomitant effect on the transmission spectrum in the LPG region. The prepared fiber sensor was highly sensitive to the change in the RI of the surrounding medium and the response time was very fast within 10 s. In addition, chemical infusion into the film was tested using a porphyrin compound, tetrakis-(4-sulfophenyl)porphine (TSPP), which could be saturated within a few min. The lowest detectable concentration of the TSPP analyte was 10 microM. The TSPP infusion led to the development of well-pronounced dual resonance bands, indicating a large increase in the optical thickness of the film. The RI of the film was dramatically increased from 1.200 to ca. 1.540.
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