Background: Stroke described as a disruption of blood flow in the brain which can lead to brain malfunction, neurological deficits, and even death. Although with good management in acute period, the incidence of recurrent stroke still increasing every year. Objectives: This study aimed to determine the dominant risk factor of stroke recurrence. Methods: This study was a cross sectional descriptive study with 274 strokes patients as samples. The samples were recruited from one of general hospital specialize in neurology disorders in Jakarta, Indonesia. Results: The result indicated a significant correlation between cardiovascular disorders, cholesterol, and activity with incidence of stroke recurrent (p<0.05). The dominant risk factor in this study was obesity event (OR = 0.616). Conclusion: Besides the dominant factor, there were 3 factors that significantly affect stroke recurrence; cardiovascular disorders, hypercholesterolemia, and physical activity. Nurses should be more aware that some patients may still have risk factors of stroke recurrence even they have discharged from hospital. With some efforts like health education and controlling the factors can help to reduce the risk of stroke recurrence.