Background and Design:Current studies link vitamin D deficiency with many autoimmune diseases. Alopecia areata (AA) is a common autoimmune dermatological disease. The aim of this study was to investigate the relationship between vitamin D levels and alopecia areata. Materials and Methods: 25-hydroxyvitamin D [25(OH)D] levels in 40 patients with alopecia areata and age, gender and skin phototypematched healthy controls were evaluated. Serum 25(OH)D levels were measured in all subjects and grouped as normal/sufficient (>30 ng/ml), insufficient (15-30 ng/ml) and deficient (<15 ng/ml). Results: Both the study and control groups were composed of 21 females and 19 males. The mean age was 31.23±7.34 (21-50) and 30. 58±7.19 (21-48), respectively. In the study group, 2.5% of patients (n=1) had normal, 15% (n=6) insufficient and 82.5% (n=33) of patients had deficient 25(OH)D levels. In the control group, 2.5% (n=1) of patients had normal, 25% (n=10) insufficient and 72.5% (n=29) of patients had deficient 25(OH)D levels. There was no statistically significant difference between the groups (p>0.05). In both groups 97.5% of patients had 25(OH)D levels below the normal range. Conclusion: Vitamin D levels in patients with AA were similar to those in the controls. This similarity may suggest that there is no relationship between vitamin D and AA. However, it may also indicate that the relationship between AA and Vitamin D is not via the level but vitamin D receptor (number and/or structure). (Turkderm 2015; 49: 50-3)
Amaç: Pitiriyazis rozea bilinmeyen etyolojisi, farklı klinik görünümleri ve farklı tanı ve tedavi seçenekleri ile ilgi çeken bir hastalık olmaya devam etmektedir. Bu çalışmada pitiriyazis rozealı hastaların klinik ve epidemiyolojik özellikleri değerlendirildi. Yöntemler: Haziran 2011-Haziran 2012 tarihleri arasında pitiriyazis rozea tanısı alan 70 hastanın demografik özellikleri ile hastalıkla ilişkili çevresel ve kişisel faktörler, hastalığın klinik özellikleri ve seyri prospektif olarak incelendi. Bulgular: Çalışma grubundaki 70 hastanın (41 kadın, 29 erkek) yaş ortalaması 25,9±15,26 (2-69) yıl idi. Hastalığın en sık görüldüğü mevsimler kış (%37,1) ve sonbahar (%27,2) olarak saptandı. Prodromal semptom öyküsü olan hastaların (n=28) en sık bildirdiği semptom halsizlik (%64,3) idi. Öncü plak 44 hastada (%62,9) gözlendi ve en sık yerleşim yeri boyun (%22,7) olarak tespit edildi. En sık bildirilen şikayet 41 hastada tespit edilen kaşıntıydı. On bir hasta atipik pitiriyazis rozea tanısı aldı. Daha önce bildirilmemiş bir boyuna lokalize pitiriyazis rozea olgusu ile dış kulak yolunda ikincil lezyonların görüldüğü bir olgu gözlendi. Hastalığın dermatoloji hastaları arasında görülme sıklığı 1/1000 olarak tespit edildi. Sonuç: Çalışmanın demografik sonuçları daha önce Türkiye'de yapılan çalışmalarda bildirilen sonuçlar ile uyumlu bulundu. Seasons in which the disease is seen most frequently were winter (37.1%) and autumn (27.2%). The most common symptom was fatigue (64.3%) in patients who had prodromal symptoms (n=28). Primary plaque was determined in 44 cases (58.6%) and the most frequent localization was neck (22.7%). The most frequent symptom was pruritus and it was present in 41 patients. Eleven patients were diagnosed as atypical pityriasis rosea. One patient demonstrated unusual presentation of pityriasis rosea with localization to neck, and another one with secondary lesions on external ear tunnel which has not been described previously. Pityriasis rosea frequency in dermatology outpatients was 1/1000. Conclusion:The demographical results of this study were consistent with the results of the previously reported studies in Turkey.
inea kapitis, kıl folikülü ve etrafındaki derinin dermatofitlerle enfeksiyonuna verilen addır. 1,2 Etken dermatofitler insan (antropofilik), hayvan (zoofilik) ve toprak (jeofilik) kaynaklı olarak sınıflandırılmakta, bulaş yolları ve farklı bölgelerde görülme sıklıkları da kaynaklarına
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