Background:Trauma is a leading cause of morbidity and mortality among individuals under 40 and is the third main cause for death throughout the world.Objectives:This study was designed to compare our modified injury scoring systems with the current injury severity score (ISS) from the viewpoint of its predictive value to estimate the duration of hospitalization in trauma patients.Patients and Methods:This analytical cross-sectional study was performed at the general referral trauma center of Bandar-Abbas in southern Iran from March 2009 to March 2010. The study population consisted of all the trauma patients referred to the emergency department (ED). Demographic data, type and severity of injury, duration of admission, Glasgow coma scale (GCS), and revised trauma score (RTS) were recorded. The injury severity score (ISS) and NISS were calculated. The length of hospital stay was recorded during the patients follow-up and compared with ISS, NISS and modified injury scoring systems.Results:Five hundred eleven patients (446 males (87.3%) and 65 females (12.7%)) were enrolled in the study. The mean age was 22 ± 4.2 for males and 29.15 ± 3.8 for females. The modified NISS had a relatively strong correlation with the length of hospitalization (r = 0.79). The formula below explains the length of hospitalization according to MNISS score. Duration of hospitalization was 0.415 + (2.991) MNISS. Duration of hospitalization had a strong correlation with MISS (r = 0.805, R2: 0.65). Duration of hospitalization was 0.113 + (7.915) MISS.Conclusions:This new suggested scale shows a better value to predict patients’ length of hospital stay compared to ISS and NISS. However, future studies with larger sample sizes and more confounding factors such as prehospital procedures, intubation and other procedures during admission, should be designed to examine these scoring systems and confirm the results of our study.
Background: Diabetes has been known as a prevalence disorder and the use of common drugs has been faced many issues with multiple limitations. This study aimed to evaluate the use of carvacrol, as a novel agent, for treatment of diabetes.
Materials and Methods:A single dose of streptozotocin (55 mg/kg body weight) was used to induce the diabetes in rats. The animals were grouped into five groups including 1. Control healthy animals; 2. Diabetic controls; 3, 4 & 5. Diabetic animals given carvacrol (5, 10 and 15 mg/kg body weight/day) in neutral sterile olive oil solution oral gavage, respectively. The levels of Malondialdehyde (MDA) and catalase, Superoxide Dismutase (SOD) and Glutathione Peroxidase (GPX) activities were evaluated. The levels of IL-1β, IL-6 and TNF-α expression in liver were assessed.Results: Administration of streptozotocin increased levels of MDA, IL-1β, IL-6 and TNF-α and also decreased activities of catalase, SOD and GPX (P<0.05). Oral administration of carvacrol, especially 15 mg/kg body weight/day, could decrease levels of MDA, IL-1β, IL-6 and TNF-α and also increase activities of catalase, SOD and GPX in comparison to diabetic control (P<0.05).
Conclusion:Carvacrol could decrease or alleviate the negative effects of carvacrol on inflammation and antioxidant status that could be attributed to antioxidant properties. It could be recommended to apply carvacrol in commercial prescription in combination with other agents or as a single agent for treatment of diabetes.
The present research aimed to compare the ultrasonography reports by the emergency service with the radiology service among suspected DVT patients. The present crosssectional and diagnostic research was conducted on 150 patients suspected of DVT in lower limb who visited the emergency section of Shahid Mohammadi Hospital in Bandar Abbas in 2017. Patients referring to the emergency section and suspected of DVT received an ultrasound sonography by the emergency service. Then the results obtained from patients' medical records were compared with the radiologists' report of Doppler ultrasound to check the presence or absence of DVT. In terms of gender, 76 patients (50.7%) were male while 74 (49.3%) were female. The precision in the diagnosis of the emergency service was 100% and the diagnostic specificity of the same service was 90.62%. The negative predictive value in the emergency service was estimated at 100% while the positive predictive value in the same service was 93.47%. The precision of 95.3% with a confidence interval of 95% was estimated at 91.1% to 99.5% (p=.000). According to the present findings, it can be concluded that performing an ultrasonography to diagnose DVT in the emergency service enjoys a high sensitivity of 100% and a negative predictive value of 100%.
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