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BackgroundThis study was designed to evaluate the effects of a 24-month period of moderate exercise on serum lipids in menopausal women.MethodsThe subjects (40–60 y) were randomly divided into an exercise group (n = 14) and a control group (n = 13). The women in the exercise group were asked to participate in a 90-minute physical education class once a week and to record their daily steps as measured by a pedometer for 24 months.ResultsMean of daily steps was significantly higher in the exercise group from about 6,800 to over 8,500 steps (P < 0.01). In the control group, the number of daily steps ranged from 5,700 to 6,800 steps throughout the follow-up period. A significant interaction between the exercise group and the control group in the changes og total cholesterol (TC), high-density lipoprotein cholesterol (HDLC) and TC : HDLC ratio could be observed (P < 0.05). By multiple regression analysis, the number of daily steps was related to HDLC and TC : HDLC levels after 24 months, and the changes in TC and HDLC concentrations.ConclusionsThese results suggest that daily exercise as well as increasing the number of daily steps can improve the profile of serum lipids.

The effects of differing durations of daily exercise on macrophage functions in mice were studied. Male ICR mice aged 4 wk were divided into five groups: a nonexercise group (control) and four exercise groups with differing daily exercise durations of 15--120 min (Exr groups). The exercise applied was 5 days/wk treadmill running at 13 m/min for 12 wk. The potentiation of the phagocytosis function of the reticuloendothelial system and the glucose consumption of peritoneal macrophages in the Exr 30, 60, and 120 groups were significantly higher than those in the control group. Superoxide anion production of peritoneal macrophages in both the absence and the presence of phorbol 12-myristate 13-acetate in the Exr 60 and 120 groups was significantly higher than that in the control group. The acid phosphatase and beta-glucuronidase activities of peritoneal macrophages in the Exr 30, 60, and 120 groups were significantly increased. These results suggest that treadmill running exercise for at least 30 min/day (30--120 min) effectively enhances macrophage functions in mice. These data provide preliminary evidence indicating that chronic exercise-induced increases in phagocytic activity exhibit a dose-dependent relationship with exercise duration.

Subjective musculoskeletal symptoms are more frequently complained about in cold store work and in related conditions than those experienced in normal temperature work. This cross sectional study was undertaken to evaluate the effects of indoor cooling and cold storage goods on the prevalence of subjective symptoms in summer. Female workers sorting cold storage goods (exposed group) were the main subjects of this study (n=47). We also included a group of female workers engaged sorting dry goods as the unexposed to cold group (n=86). Work load for the two groups were estimated according to the recommended criteria. A selfadministered questionnaire covering age, occupational career, smoking, alcohol drinking and physical exercise, present or past history of diseases, individual protective measures against cold or heat, and subjective symptoms (60 items) was used. The air temperature of the site at the start of working time for the workers sorting cold storage goods was 22.2°C which was significantly lower than those measured for the other two work places (25.4°C and 25.4°C) of the unexposed to cold group. Environmental temperatures at the foot level at the sorting workshop of cold storage goods and dry goods were ca.16°C and 26°C all day, respectively. The surface temperatures of cold storage goods were between -2.8°C and 9.4°C. The surface temperature of dry goods was 26.5°C. Among the working characteristic items, only daily working hours in the exposed group (5.6 ± 0.6 h) were significantly longer than those in the unexposed to cold group (4.6 ± 0.9 h) (p<0.01). The prevalence rates of finger cold sensation, stiffness in the fingers, pain in the wrist, pain in the elbow, back dullness, back pain, low-back cold sensation, foot cold sensation and pain in the foot in the exposed group were significantly higher than those in the unexposed to cold group (p<0.05 or p<0.01). Pain in the fingers, numbness in the fingers, pain in the foot and foot numbness due to the cold in the exposed group were significantly higher than those in the unexposed to cold group (p<0.05 or p<0.01). These results suggest that indoor cooling and/or job activities related to cold storage goods could, to some extent, affect peripheral circulatory disturbances; and it could be regarded as a factor related to musculoskeletal symptoms among the exposed workers.

In the present study, a survey on subjective symptoms and hot prevention measures in summer was conducted in 204 male traffic control workers and 115 male construction workers. Work loads of traffic control workers and construction workers were estimated at RMR 1-2 and RMR 2-4, respectively. A self-administered questionnaire was used to collect information on age, occupational career, working habit, present or past history of diseases, individual preventive measures to the heat, and subjective symptoms in the summer. Daily working hours in the sunshine of the traffic control workers were significantly longer than those of the construction workers. Prevalence rates of changing clothes frequently, avoiding direct exposure of face and neck to sunlight using towel like materials, and wearing sunglasses in the traffic control workers were significantly lower than the construction workers. Prevalence rates of symptoms in the upper extremities in the traffic control workers were significantly lower than those in the construction workers. Prevalence of work difficulty due to hot weather during work in the traffic control workers was significantly lower than the construction workers. On the basis of the results obtained, some preventive countermeasures to improve working environment are presented.