Background and Aim: Moral sensitivity is a feature that enables a person to recognize his/her moral conflicts and to understand the results of moral judgment about others. Considering that this issue is more important in the ICUs and since observance of patients' rights is one of the aspects of moral care, this study aimed to determine the relationship between nurses' moral sensitivity and respect for patients' rights in ICUs in 2016. Materials and methods:In this descriptive-correlational study, 260 nurses working in ICUs of hospitals affiliated to Tehran University of Medical Sciences were selected by accessible method. To collect data, the Lutzen's Moral Sensitivity Questionnaire and Researcher-made Patients' Rights Questionnaire were used. The Data were analyzed using SPSS 20 and statistical tests. Ethical considerations: Participation in the study was optional and informed written consent was obtained from nurses to participate in the study. In addition, the information confidentiality of the participants was observed. Findings: The mean of moral sensitivity of nurses in intensive care units (160.58±18.30) and respect for patients' rights by them (12.19±127.81) were higher than average. There was a direct significant correlation between the nurses , moral sensitivity and the degree of observance of patient's rights in ICUs (P<0.0001 and r=0.326). Conclusion: Regarding the observed relationship between moral sensitivity and observance of patients' rights, it is suggested to adopt appropriate strategies to improve the observance of patients' rights in order to increase the level of moral sensitivity of nurses and provide high-quality care.