Respecting human privacy creates holistic patient-oriented care. The aim of this study was to determine the hospitalized patients' viewpoints concerning their privacy observance. This descriptive, analytic and cross-sectional research administered on 370 patients that selected through the random-stratified sampling in an educational hospital in the Khorramabad in Iran in 2013-2014. Data collected by a questionnaire regarding observance of the patients' privacy by hospital staff, including physical-corporeal, psycho-mental, and informational domains. Data were gathered through constructed interview and analyzed with Independent t-test, One-way ANOVA and Pearson correlation statistical tests. The human privacy of the patients and its physical-corporeal and informational domains were sometimes observed, while the psycho-mental domain was often respected. The privacy observance was significantly lower for men (p=0.000), patients in the emergency department (p=0.000), and the patients who spoke with a local accent (p= 0.016). It seems necessary to train and reinforce the health care providers to respect patients' physical-corporeal and informational privacy consciously, to observe male patients' privacy and   using better interpersonal communication skills in dealing with non-Persian language patients. It also seems the structure and design of emergency departments need to be revised in order to protect the privacy of the patients.