Background & Objective: Diabetes mellitus (DM) is one of the most common metabolic disorders that cause a high annual cost of patients care and health services in a society. Given the fact that DM management is very important, the present study aims to investigate the effect of combined therapy with fenugreek and nutrition training based on Iranian traditional medicine on FBS, HgA1c, BMI, and waist circumference in type 2 diabetic patients. Materials & Methods: This randomized double blinded clinical trial was conducted on patients with type 2 diabetes in Tehran (Iran) during 2017. Patients were randomly divided into four groups, including: G1 [fenugreek powder (10g/two times per day) with nutrition training), G2 [wheat flour (placebo) with nutrition training), G3 [fenugreek powder (10g/two times per day) without nutrition training], and G4 [wheat flour (placebo) without nutrition training]. Results: This study was done on 125 patients (43% male and 57% female). There was no significant difference in demographic characteristics of all groups. The mean of FBS in G1, G2, G3 and G4 significantly decreased by 62, 12, and 23 units, respectively (P<0.001). The mean of HbA1c in groups G1, G2, and G3 declined by 0.77, 0.31 and 0.5 units, respectively. The mean of BMI in groups G1, G2, and G3 decreased by 1.38, 0.82 and 0.89 units, respectively. Furthermore, waist circumference reduced in all of three groups by 7.11, 3.8 and 3.18 units, respectively. There was no significant change in mean value of these parameters in G4 group. Conclusion: Given the positive effect of fenugreek and nutrition training on FBS, HbA1c, BMI, and waist circumference, it can be suggested for blood glucose control in diabetic patients. Interestingly, combined therapy with fenugreek and nutrition training was more effective in reducing blood glucose, indicating the importance of this combined therapy for blood glucose control in DM patients.

Background: Diabetes mellitus is a major cause of death globally. It causes multiple problems in various organs and incurs heavy costs for patients and the community health system.The present study was conducted to evaluate the effect of fenugreek intake on fasting blood sugar (FBS), HbA1C, body mass index (BMI), waist circumference, blood pressure and quality of life of type 2 diabetes mellitus (T2DM) patients. Materials and Methods: This randomized, double-blinded clinical trial study was conducted on patients with T2DMin Tehran, Iran in 2018. The treatment group received 5 g of fenugreek powder,and the placebo group received 5 g of wheat flour twice daily for two months before meals. Results: This study was performed on 62 patients (50% male and 50% female). Both groups had similar demographic characteristics. The results showed a significant difference between the mean FBS (P<0.001), HgA1C (P<0.001), BMI (P<0.001), waist circumference (P<0.001), diastolic blood pressure (P=0.005), and quality of life (P=0.015). There was no significant difference in mean systolic blood pressure (P=0.189) between groups.  Conclusion: Given the positive effect of fenugreek on FBS, hemoglobin, HbA1C, BMI, waist circumference, blood pressure and quality of life, it can be recommended for controlling blood glucose in diabetic patients. [GMJ.2019;8:e1432]

Background: Diabetes mellitus is a major cause of death globally. It causes multiple problems in various organs and incurs heavy costs for patients and the community health system. The present study was conducted to evaluate the effect of fenugreek intake on fasting blood sugar (FBS), HbA1C, body mass index (BMI), waist circumference, blood pressure and quality of life of type 2 diabetes mellitus (T2DM) patients. Materials and Methods: This randomized, double-blinded clinical trial study was conducted on patients with T2DM in Tehran, Iran in 2018. The treatment group received 5 g of fenugreek powder, and the placebo group received 5 g of wheat flour twice daily for two months before meals. Results: This study was performed on 62 patients (50% male and 50% female). Both groups had similar demographic characteristics. The results showed a significant difference between the mean FBS (P<0.001), HgA1C (P<0.001), BMI (P<0.001), waist circumference (P<0.001), diastolic blood pressure (P=0.005), and quality of life (P=0.015). There was no significant difference in mean systolic blood pressure (P=0.189) between groups. Conclusion: Given the positive effect of fenugreek on FBS, hemoglobin, HbA1C, BMI, waist circumference, blood pressure and quality of life, it can be recommended for controlling blood glucose in diabetic patients.[GMJ. 2019;inpress:e1432]