Melamine is widely used as a chemical in food industry and may lead to kidney damage. The aim of this study was to determine melamine and pH value of 80 canned tuna fish samples of four different brands (A, B, C, D) sold in Ankara, Turkey. Quantitative determination of melamine in canned tuna fish samples was carried out by capillary zone electrophoresis with diode array detector (CZE-DAD). The limits of detection and quantitation for melamine were found to be 0.21 mg kg -1 and 0.68 mg kg -1 , respectively. The proposed method was successfully applied for the analysis of melamine in canned tuna fish samples by mean recovery with 104.7% in oily and 107.6% for light samples. Melamine levels were found as <0.68 mg kg -1 (LOQ value) in all samples analysed during the period of the study. The mean pH values (±SE) of the samples for the A, B, C and D brands were determined to be 5.89 ± 0.02, 5.86 ± 0.01, 5.83 ± 0.02 and 5.82 ± 0.02, respectively. As a result, present study shows that the presence of melamine of canned tuna fish obtained during the period of study do not pose a health risk to consumers.

A new capillary electrophoresis method was developed for the simultaneous determination of dexpanthenol (DEX), lidocaine (LID), and mepyramine (MEP) in pharmaceutical preparations. The best results were obtained using 20 mM (pH 3.0) phosphate buffer as the background electrolyte. Separation was obtained using a fused-silica capillary (75 µ m internal diameter, 50 cm total length, 41 cm effective length) and a potential of +30 kV at 20 • C. Standards and samples were injected using a pressure injection at 50 mbar for 5 s and the analytes were monitored at a detection wavelength of 200 nm. Under optimum conditions, migration times were 2.457 min for MEP, 3.520 min for LID, and 7.363 min for DEX. The method was linear over the ranges of 25-200 µ g mL −1 for DEX, 7.5-60 µ g mL −1 for MEP, and 7.5-60 µ g mL −1 for LID. Limit of detection (LOD) values were 0.8 µ g mL −1 for MEP, 1.8 µ g mL −1 for LID, and 3.1 µ g mL −1 for DEX. The developed method is accurate, precise, sensitive, selective, and repeatable.