The retinal vessels may become susceptible to damage due to retinal tear, retinal detachment, sickle cell insult, aneurysms, macular degeneration, trauma, and veinous occlusion. These conditions could cause retinal bleeding, also known as vitreous hemorrhage. PubMed database was used for articles selection, papers were obtained and reviewed. PubMed database was used for articles selection, and the following keys terms: vitreous hemorrhage, pathophysiology, risk factors, clinical features, diagnosis, and management. The vascular insult occurs in the surrounding potential space around the vitreous. This insult is a result of traumatic injury to the retina or the vessels or ischemic condition of the vessels due to an abnormal vessel formation. Immediate diagnosis and management of the bleeding are needed, especially in cases with deteriorating vision and continued bleeding. Management options include watchful waiting, laser therapy, cryotherapy, antivascular growth injections, and vitrectomy. Vitreous hemorrhage is a medical emergency that could lead to severe and permanent visual loss if not diagnosed and managed fastidiously. The disease may often resolve on its own and vision is restored, however, medical and surgical therapy might be urgently required in selected cases.