Phenolic derivatives are one of the most important compounds that were found in secondary metabolites in plants. According to their various applications in agriculture, food, chemical and pharmaceutical industries, interests in reviewing different procedures of extraction of these compounds from plants have increased. In this chapter, we would like to have an overview on the extraction procedures that have been used in isolating phenolic compounds from plants until this time, including liquid-liquid extraction (LLE), ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE) and supercritical fluid extraction (SFE). In the following, advantages and disadvantages of these techniques and methods will be discussed and explained. In addition, in the last part of this chapter, various methods for purification and identification of phenolic compounds will be presented.