polycistic ovaries, with the exclusion of other aetiologies 2 . According to the National Institutes of Health, basic diagnostic criteria should be the presence of hyperandrogenism and chronic oligoanovulation, with the exclusion of other causes of hyperandrogenism such as adultonset congenital adrenal hyperplasia, hyperprolactinaemia and androgensecreting neoplasms 3 . A consensus conference held in Rotterdam agreed on the appropriateness of including ultrasound morphology of the ovaries as a further potential criteria to define the PCOS but also established that at least two of the following criteria are sufficient for the diagnosis: oligo and/or anovulation, clinical and/or biochemical signs of hyperandrogenism and polycystic ovaries at ultrasound 4 . The pathophysiology of PCOS may have a genetic component although it can be suggested that the main factors responsible for the increasing prevalence of PCOS are related to the influence of the environment, including dietary habits, behaviour and other still undefined factors 1 . The clinical features of PCOS are heterogeneous and may change throughout the lifespan, starting from adolescence to postmenopausal age 5 . This is largely dependent on the influence of obesity and metabolic syndrome, which consistently affect most women with PCOS 6 . This represents an important factor in the evaluation of the PCOS throughout life and implies that the PCOS by itself may not be a hyperandrogenic disorder exclusively restricted and relevant to young and fertileaged women but may also have some health implications later in life.Whereas hyperandrogenism and menstrual irregularities represent the major complaints in young women with the PCOS, symptoms related to androgen excess, oligomenorrhoea or amenorrhoea and, particularly, infertility are the main complaints of adult women with PCOS during the reproductive age. Obesity has an important impact on the severity of these manifestations in proportion to its degree and particularly in the presence of the abdominal phenotype 6 . In addition, there is consistent evidence that it renders affected women more susceptible to develop type II diabetes, with some differences in the prevalence rates between countries and, potentially, in favouring the development of cardiovascular diseases 1 .The present study was carried out to evaluate the characteristics and laboratory examination findings of PCOS patients attending a tertiary hospital in Dhaka city. Abstract: Polycystic ovary syndrome (PCOS) is a common condition

Infertility is a major public health concern accounting for 10%-15% all

Background: The objective of the study was to explore the correlation and discordance of anti-mullerian hormone (AMH) and follicle stimulating hormone (FSH) in the selected population of premature ovarian insuffiency and diminished ovarian reserve.Methods: This was a retrospective analysis of the data obtained from the women who presented to the Gynae Endocrine Clinic of the Infertility unit of the Department of Obstetrics & Gynaecology from 2015 to 2017. Discordance was defined as abnormal basal FSH (>10 IU/l) with assuring AMH (>1 ng/ml). Statistical analysis was done with SPSS version 23.Results: There were 36 women with premature ovarian insufficiency and 35 women with diminished ovarian reserve. The correlations between basal FSH and AMH are not significant. AMH values are relatively higher in younger age groups. There are extreme high outliers in both POI and DOR groups, more in younger age group. The discordance between AMH and basal FSH was more in women categorized to have diminished ovarian reserve, compared to women with premature ovarian insufficiency.Conclusions: Those women who are younger than 35 years and have high FSH combined with reassuring AMH should be counseled with care regarding the prognosis of their treatment.

Objective: This study tried to evaluate association of other factors of subfertility in women suffering from polycystic ovarian syndrome (PCOS). Methods: Fifty subfertile women suffering from PCOS attending infertility unit of the Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, during July 2010 and June 2011, were evaluated. Results: In out study, Age, BMI and duration of marriage range was 20 38 years, 17.70 33.20 kg/m2 and 1 16 years, respectively. Serum FSH was normal (1.0 10.0 mIU/ml) in all 50 (100%) women. Hyperprolactinaemia (serum prolactin >25 ng/ml) was seen in 60%. Hypothyroidism (serum TSH >4 ìIU/ml) was seen in 74% women. Serum LH (>10 mIU/ml) was raised in 74%. USG finding of lower abdomen was abnormal in 75% cases. Conclusion: This study concludes that hyperprolactinaemia and subclinical hypothyroidism were associated causes of subfertility other than PCOS. DOI: http://dx.doi.org/10.3329/jbcps.v31i3.20980 J Bangladesh Coll Phys Surg 2013; 31: 140-143

DOI: http://dx.doi.org/10.3329/bjch.v34i2.10221BJCH2010; 34(2): 70-72