SummaryAdrenal haemorrhage is a rare cause of adrenal crisis, which requires rapid
diagnosis, prompt initiation of parenteral hydrocortisone and haemodynamic monitoring
to avoid hypotensive crises. We herein describe a case of bilateral adrenal
haemorrhage after hemicolectomy in a 93-year-old female with high-grade colonic
adenocarcinoma. This patient’s post-operative recovery was complicated by an
acute hypotensive episode, hypoglycaemia and syncope, and subsequent computed
tomography (CT) scan of the abdomen revealed bilateral adrenal haemorrhage. Given her
labile blood pressure, intravenous hydrocortisone was commenced with rapid
improvement of blood pressure, which had incompletely responded with fluids. A
provisional diagnosis of hypocortisolism was made. Initial heparin-induced
thrombocytopenic screen (HITTS) was positive, but platelet count and coagulation
profile were both normal. The patient suffered a concurrent transient ischaemic
attack with no neurological deficits. She was discharged on a reducing dose of oral
steroids with normal serum cortisol levels at the time of discharge. She and her
family were educated about lifelong steroids and the use of parenteral steroids
should a hypoadrenal crisis eventuate.Learning points:Adrenal haemorrhage is a rare cause of hypoadrenalism, and thus requires
prompt diagnosis and management to prevent death from primary adrenocortical
insufficiency.Mechanisms of adrenal haemorrhage include reduced adrenal vascular bed
capillary resistance, adrenal vein thrombosis, catecholamine-related
increased adrenal blood flow and adrenal vein spasm.Standard diagnostic assessment is a non-contrast CT abdomen.Intravenous hydrocortisone and intravenous substitution of fluids are the
initial management.A formal diagnosis of primary adrenal insufficiency should never delay
treatment, but should be made afterwards.
In an in vivo porcine survival model of esophageal endoscopic mucosal resection, the use of MCC resulted in significantly less deep thermal ulceration, necrosis, and acute inflammation compared with LPCC. MCC should be used in preference over LPCC for esophageal endoscopic resection.
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