Objective: To assess the use of C-reactive protein in patients with STEMI and NSTEMI to differentiate between the type of myocardial infarction at our hospital. Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Medicine, Pak Emirates Military Hospital, Rawalpindi and Armed Force Institute of Cardiology & National Institute of Heart Disease, from Mar 2020 to Feb 2022. Methodology: Patients diagnosed with MI by a consultant cardiologist were included in the study. They underwent all baseline investigations, including C reactive protein, at the time of presentation to a cardiac emergency. The treating consultant diagnosed MI (ST elevation or non-ST elevation) based on electrocardiogram findings. Values of C reactive protein and other socio-demographic variables were compared in both groups (patients with and without ST elevation MI). Results: A total of 3500 patients with myocardial infarction were included in the final analysis. 2219(63.4%) had NSTEMI,while 1281(36.6%) had STEMI. Statistical analysis showed that C-reactive protein levels were not statistically different in both groups (p-value-0.375), but gender and Creatinine kinase myocardial bound levels were different in patients with non-ST elevation myocardial infarction and ST-elevation myocardial infarction (p-value<0.001). Conclusion: Raised levels of C reactive protein were not statistically significantly different in ST-elevation myocardial infarction and non-ST elevation myocardial infarction patients. CKMB may give a better clue for differentiation between these two types of myocardial infarctions.Keywords: Creactive protein, Non-ST-elevation myocardial infarction, ST-elevation myocardial infarction.
Objective: To look for the low levels of haemoglobin and ferritin among the patients of chronic kidney disease (CKD) Stage-5 not undergoing dialysis and factors related to the presence of low levels of haemoglobin and ferritin. Study Design: Cross-sectional study. Place and Duration of Study: Department of Nephrology, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Feb 2019 to Jan 2021. Methodology: A total of 800 cases were included in the study, diagnosed as chronic kidney disease Stage-5 in the nephrology outpatient department (OPD) by a consultant nephrologist who did not require hemodialysis. Haemoglobin and ferritin levels were recorded in all patients at the time of assessment in the outpatient department. In addition, the relationship of various factors was assessed with low haemoglobin and ferritin among the study participants. Results: Out of 800 non-dialysis chronic kidney disease patients in the study, 421(52.7%) patients were males and 379(46.3%) were females. Of the participants, 471(58.9%) had either low ferritin or hemoglobin levels, while 329(41.1%) did not show low haemoglobin and/or ferritin levels. Long duration of illness and female gender was significantly associated with low haemoglobin/ferritin levels among the non-dialysis patients of chronic kidney disease Stage-5 (p-value<0.05). Conclusion: Low levels of hemoglobin and ferritin were found in most patients suffering from chronic kidney disease Stage-5 and not undergoing hemodialysis. Therefore, special attention should be paid to female patients and patients with a longer duration of chronic kidney disease.
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