Purpose To investigate the prevalence of spontaneously developed tail swellings (SDTS) in human sperm samples that are commonly encountered in the laboratory, and their influence on the hypo-osmotic swelling test (HOS-test). Methods Ejaculated, epididymal, and testicular sperm were evaluated for SDTS. Further, HOS-test scores were compared with those of vital stains using column washed sperm maintained in the laboratory. Results SDTS, at <10%, was present in all types of sperm samples. The highest and lowest occurrences of SDTS were found in cryopreserved sperm, and column-washed sperm respectively. SDTS can inflate the HOS-test score, and so lower the accuracy of the HOS-test. However, the HOS-test efficiency can be improved by assessing SDTS in the sample. Conclusion HOS-test and vital stain cannot be used interchangeably in all circumstances for sperm viability determination. The accuracy of the HOS-test can be enhanced by incorporating SDTS as a correction factor.
Cochlear implant users hear pitch evoked by stimulation rate, but discrimination diminishes for rates above 300 Hz. This upper limit on rate pitch is surprising given the remarkable and specialized ability of the auditory nerve to respond synchronously to stimulation rates at least as high as 3 kHz and arguably as high as 10 kHz. Sensitivity to stimulation rate as a pitch cue varies widely across cochlear implant users and can be improved with training. The present study examines individual differences and perceptual learning of stimulation rate as a cue for pitch ranking. Adult cochlear implant users participated in electrode psychophysics that involved testing once per week for three weeks. Stimulation pulse rate discrimination was measured in bipolar and monopolar configurations for apical and basal electrodes. Base stimulation rates between 100 and 800 Hz were examined. Individual differences were quantified using psychophysically derived metrics of spatial tuning and temporal integration. This study examined distribution of measures across subjects, predictive power of psychophysically derived metrics of spatial tuning and temporal integration, and the effect of training on rate discrimination thresholds. Psychophysical metrics of spatial tuning and temporal integration were not predictive of stimulation rate discrimination, but discrimination thresholds improved at lower frequencies with training. Since most clinical devices do not use variable stimulation rates, it is unknown to what extent recipients may learn to use stimulation rate cues if provided in a clear and consistent manner.
Speech segregation in background noise remains a difficult task for individuals with hearing loss. Several signal processing strategies have been developed to improve the efficacy of hearing assistive technologies in complex listening environments. The present study measured speech reception thresholds in normal-hearing listeners attending to a vocoder based on the Fundamental Asynchronous Stimulus Timing algorithm (FAST: Smith et al. 2014), which triggers pulses based on the amplitudes of channel magnitudes in order to preserve envelope timing cues, with two different reconstruction bandwidths (narrowband and broadband) to control the degree of spectrotemporal resolution. Five types of background noise were used including same male talker, female talker, time-reversed male talker, time-reversed female talker, and speech-shaped noise to probe the contributions of different types of speech segregation cues and to elucidate how degradation affects speech reception across these conditions. Maskers were spatialized using head-related transfer functions in order to create co-located and spatially separated conditions. Results indicate that benefits arising from voicing and spatial cues can be preserved using the FAST algorithm but are reduced with a reduction in spectral resolution.
The precedence effect (PE) enables the perceptual dominance by a source (lead) over an echo (lag) in reverberant environments. In addition to facilitating sound localization, the PE can play an important role in spatial unmasking of speech. Listeners attending to binaural vocoder simulations with identical channel center frequencies and phase demonstrated PE-based benefits in a closed-set speech segregation task. When presented with the same stimuli, bilateral cochlear implant users did not derive such benefits. These findings suggest that envelope extraction in itself may not lead to a breakdown of the PE benefits, and that other factors may play a role.
This study examined the effects of context on the production of vowels spoken by children of different ages in isolation and in a carrier sentence. Vowels were extracted from a database of hVd syllables produced by 207 native English talkers from the North Texas region, ranging in age from 5 to 18 years with approximately equal numbers of males and females. Preliminary analysis of a subset of the database (around 25% of talkers) showed a systematic reduction in vowel duration with increasing age for syllables in isolation. Vowels in sentence context were on average 30% shorter than in isolated syllables, and durations were less closely linked to age group. Formant frequencies (F1–F3) showed similar patterns for vowels in isolated syllables and sentences, and decreased as a function of age as expected. However, measures of formant movement across the vowel (from 20 to 80% of the vowel duration) revealed increased F1 and F2 movement for syllables in isolation compared to those produced in carrier sentences. A comprehensive analysis of the database will be presented and implications for vowel recognition will be discussed.
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