Introduction: Peetha Saireyaka tablet (PST) is a herbal formulation widely used in Ayurvedic clinical practice with multi fold benefits, specifically to combat chronic tonsillitis in children. There is no work on record on formulation and standardization aspect of herbal drug, Peetha Saireyaka tablet. This paper highlights the preparation, physico-chemical characterization, TLC and HPTLC densitogram profiling of Peetha Saireyaka tablet which can be applied for authentication of this herbal formulation.
Methods: The roots of Peetha Saireyaka (Barleria prionitis Linn.) were authenticated botanically. The tablets were prepared at certified pharmacy and subjected for detailed physico-chemical and HPTLC analyses.
Results: Set of standardization parameters were derived for Peetha Saireyaka tablet by physico-chemical characterization. The tests proposed would serve as diagnostic parameters for the identity of this herbal formulation. HPTLC fingerprint profile which can serve as a fingerprint for the identification of the formulation has been obtained.
Conclusion: The proposed method of making tablet from roots of Peetha Saireyaka (Barleria prionitis Linn.) will aid in yielding concentrated medicament with the same efficacy as per the classically proposed drug dosage at lower dose. Standards for the herbal formulation has been developed for the quality check of the formulation.
Background:
Cerebral Palsy (CP), is umbrella term which encompasses a broad spectrum of neurological impairments which requires multiple line of treatment. Ayurveda interventions for improving the motor disabilities can contribute in bringing out a better result in this condition.
Objective:
To evaluate the effect of Ayurveda treatment modalities in motor disabilities of children with cerebral palsy (CP).
Materials and Methods:
A single-centered, open-labeled, prospective, clinical trial was conducted at a tertiary care teaching hospital attached to Ayurveda Medical College located in district headquarters. Overall, 15 subjects affected with CP were administered with Ayurveda treatment modalities that are inclusive of Udwarthana (dry powder massage), Sarvanga Abhyanaga (oil massage), Sarvanga Parisheka (pouring of warm liquid over a desired body part), Shirodhara (pouring of warm liquid over the head), Upanaha (warm poultice), Matra Basti (medicated enema), and Karnapoorana (administering warm oil into the ear canals) for a period of 15 days. The subjects were assessed before and after treatment for spasticity, muscle power, and range of movements of joints. The data were collected by using a case report form designed for the study. Such collected data were tabulated and analyzed by using Statistical package for social sciences (SPSS, version 20) by using an appropriate statistical test.
Results:
The intervention was found to be effective in reducing spasticity as well as in improving the movement of joints at P < 0.05.
Conclusion:
Holistic Ayurveda treatment modalities can be beneficially implemented for treating spasticity in children with CP.
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