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Background: Hepatocellular carcinoma is the most common primary liver malignancy and considered as the fifth most common cancer worldwide. Resection and liver transplantation have a high survival in adequately selected patients, however locoregional ablative therapeutic techniques has several advantages over surgery like hepatic parenchymal preservation and overall have less morbidity and mortality. Aim of Study: The aim of this study was to evaluate the role of diffusion and dynamic MR imaging in the assessment of the treatment response of hepatocellular carcinoma after radiofrequency ablation according to the LI-RADS treatment response v2018. Patients and Methods: A retrospective study included 40 patients with 45 HCC lesions underwent radiofrequency ablation and followed-up by dynamic and diffusion MR imaging. The data were collected from the PACS of Radiology Department, Cairo University Hospitals. The MR images were assessed according to LI-RADS 2018 treatment response algorithm. Results: According to LI-RADS treatment response criteria, dynamic MRI has sensitivity of 100%, specificity 95.8%, Positive Predictive Value (PPV) 94.1% and Negative Predictive Value (NPV) 100% compared to sensitivity of 64.3%, specificity 95.8%, PPV 90% and NPV 82.1% for the diffusion weighted images in the detection of tumoural viability. Arterial Phase Hyperenhancement (APHE) was found in 87.5% of viable lesions while delayed wash out was found in 100% of the viable lesions. Conclusion: Dynamic MRI is the cornerstone in the assessment of treatment response of hepatocellular carcinoma to radiofrequency ablation. Arterial phase hyperenhancement and delayed wash out are the main criteria for diagnosis of tumoural viability according to LI-RADS treatment response algorithm. Diffusion imaging and ADC measurement are good negative techniques for exclusion of tumoural activity and also can confirm the dynamic findings in viable cases.

Background: Laryngeal cancer comprises 2 to 5% of all malignant diseases diagnosed annually worldwide. Cartilage invasion by the laryngeal cancer is of great importance through the staging of laryngeal carcinoma according to TNM classification and has a great impact on management plan. There is a scarcity in the published literature regarding the comparison between MRI and CT for assessment of cartilage involvement. Aim of Study:To assess the validity of MRI and to compare this with CT findings in predicting inner and outer thyroid cartilage laminae invasion in patients with laryngeal carcinoma.Patients and Methods: The present study was an observational analytical study that was carried out from January 2018 to June 2019 at the Radiology Department of Faculty of Medicine, Cairo University. A total of 30 patients with laryngeal carcinoma were included. CT and MRI was done for all patients.Results: There was a good agreement between readers in CT interpretation in term of inner lamina involvement (K=0.78) and very good agreement in term of outer lamina involvement (K=0.87). While in MRI interpretation, there was a very good agreement between readers in term of inner lamina involvement (K=0.83) and outer lamina involvement (K=0.92). However higher accuracy & confidence levels were found on interpretation of both CT and MRI together. We found a higher interobserver agreement between interpretation of CT and MRI together (K=1.00). Conclusion:MRI showed high validity and precision in detecting inner and outer thyroid lamina invasion by laryngeal caner than CT scan. We found that the combination of CT and MRI together was associated with more accuracy and confidence level for the readers.