1Air dried whole coffee fruits, beans and husks from China, India and Mexico were analysed 2 for their chlorogenic acids (CGA), caffeine, and polyphenolic content. Analysis was by 3 HPLC and Orbitrap exact mass spectrometry. Total phenol, total flavonol and antioxidant 4 capacity were measured. 5The hydroxycinnamate profile consisted of caffeoylquinic acids, feruloyquinic acids, 6 dicaffeoylquinic acids and caffeoyl-feruloylquinic acids. A range of flavan-3-ols as well as 7 flavonol conjugates were detected. The CGA content was similar for both Mexico and India 8 coffee fruits but was much lower in China samples. Highest levels of flavan-3-ols were 9 found in the Indian samples whereas Mexico samples contained the highest flavonols. 10Amounts of CGAs in the beans were similar to those in the whole fruits, but flavan-3-ols and 11 flavonols were not detected. The husks contained the same range of polyphenols as in the 12 whole fruits. Highest levels of caffeine were found in the Robusta samples. 13 14

Albumin-bound nanoparticles of practically water-insoluble antimalarial lead greatly enhance its efficacy.

Cymbopogon citratus, universally known as Lemongrass is a small herbaceous plant of Poaceae family. It is used as traditional medicine for treatment of numerous diseases such as fever, sore throats, cough, laryngitis, bronchitis, oral candiasis, body ache, head ache, digestive problems etc. This study deals with the antioxidant activities such as DPPH and FRAP of mehanol extract of lemon grass leaves followed by quantitative analysis of total phenolics (TPCs) and flavonoids (TFCs) content. Antimicrobial activity of the extract was also been tested to highlight the medicinal values. The methanol extract showed significant antioxidant activity using DPPH and FRAP (26.03±1.60 μM; 922.43 μM trolox/100 g dry weight, respectively) compare to the standard Trolox.C. citratus extract has phenolic and flavonoid content as 130.33±1.23; 193.63±4.63, respectively. The results showed that extract of C. citratus exhibited maximum zone of inhibition (35mm) against Bacillus subtilis. at the highest concentration 150mg/ml methanol extract.

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