Viral infections during pregnancy have been associated with adverse pregnancy outcomes and birth defects in the offspring. Viruses rarely cross the placental barrier, but when the virus does reach the fetus, it can result in severe birth defects such as microcephaly or even fetal death. Human herpes virus 7 (HHV-7) is thought to cause severe complications is spontaneous abortion. These experiments were conducted to study the effect of human herpes virus -7 on the pregnant women and cause abortion. This case control study was done for 100 patients including different ages that range from 18-47 age that sever recurrent miscarriage. Also the study includes 50 apparently healthy control (AHC) this age were similar with the patients age. The specimens were collected during winter from August 2021 to February 2022. Endometrium; Cervical swabs; fetal fluids swabs as well as Blood specimens were collected and processed to extract viral genome.  The mean age of the patients with RPL was (‎32.70±12.41 years) was less than the mean age of the AHC (30.67 ± 11.17 years). There are non-significant statistical differences (p=0.47) between RPL and AHC.