Cancer is one of the most death causing diseases and the number of cases rising around the world. So, there is a developing demand to get a durable cure to treat this awful disease. Currently, conventional techniques such as chemotherapy are not suitable for their destructive post-treatment outcomes and sometimes it is not a budget-friendly option to every person. Various medicinal plant acquired metabolites have become the core of interest due to their fewer side effects and variable application in averting cancer. Bangladesh is an agricultural country, and a remarkable variety of medicinal plants is available here with significant anticancer properties. Numerous natural products and their analogs have been recognized as potent anticancer agents. This review has been plotted to explore diverse medicinal plants of Bangladesh with anticancer activity and their effectual compounds to treat cancer. Based on the results of the various articles indexed in Google Scholar, PubMed, Scopus etc. a number of plants have been reported to be used in the treatment and prevention of different kinds of cancer disorders. The plants include Phyllanthus emblica, Terminalia chebula, Withania somnifera, Azadirachta indica, Zingiber officinale, Allium sativum, Cinnamomum verum, Nigella sativa, Catharanthus roseus, Cannabis sativa, Camellia sinensis, Hibiscus rosa-sinensis, Solanum lycopersicum etc. Different anticancer metabolites found in these plants has potential to treat different cancer. Phytochemical investigations have scrutinized the therapeutic effects of medicinal plants constructive on numerous cancers and their possible mechanisms of action and clinical effects.
The discovery of CAR T cell immunotherapy, also known as chimeric antigen receptor (CAR) T cell immunotherapy, has added a new dimension to the world of cancer treatment. This is a gene-based treatment in which T cells from the patient's body are taken and genetically engineered
Antibiotic resistance is global trouble and in the megacities, it is causing more rapidly due to the misuse and overuse of antibiotics. This systematic evaluation used to be carried out to summarize the contemporary day kingdom of affairs of antibiotic resistance in Dhaka, to emerge as aware of gaps in close observation, and to prink tips primarily based on honesty and surely on the findings. Google scholar, PubMed, and Bangladeshi journals online have been searched for the use of applicable key phrases to select articles connected to antibiotic resistance in Dhaka, Bangladesh published between 2004 to 2020. The resistance of a bacterium to a given drug was once added as the median resistance and interquartile fluctuate. Forty-one articles have been blanketed in this systematic review. Antimicrobial susceptibility trying out used to be once as quickly as carried out via disk diffusion approach in 97.56% of studies, at the equal time as the clinical and laboratory standards institute suggestions had been accompanied in 92.68%. Data concerning the susceptibility attempting out method and furnish of sickness (hospital/community) had been absent in 12.19%, 10.52%, and 90.24% of the research, respectively. An excessive prevalence of resistance used to be detected in most examined pathogens, and many of the normal first-line pills have been the most importantly ineffective. Resistance to carbapenems was once low in most cases. An excessive incidence of resistance to most antibiotics used to be detected, alongside necessary gaps in surveillance and facts gaps in the methodological data of the show up to be up.
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