At the site of continuous rolling of lithium battery electrode, most of its correction units use traditional PID control algorithms, coupled with the complex structure of the rolling equipment and the large number of control system actuators, result in the deviation of the pole piece position being controlled within 10mm only. In order to avoid the undesirable industrial problems caused by untimely correction and insufficient control accuracy, this paper proposes a control strategy for lithium battery roll press deflection device with the introduction of GA(Genetic Algorithm) optimized integral separation PID. For the problems of poor self-adaptive capability of deflection control and interference with equipment and environment during the rolling process. Analyze the causes of runout of the pole piece and the structure of the deflection correction system, establish a mathematical model and an integral separation fuzzy PID controller to realize the deflection control. Optimize the key parameters of the controller using GA to improve the control accuracy and performance of the deflection control. Simulations and experiments show that the deviation control strategy proposed in this paper can reduce the position deviation of the polar strip to within 4mm, which can effectively improve the deviation correction accuracy and the anti-interference capability of equipment operation, and also provide a good solution for the deviation control of other large and complex mechanical equipment.