As buildings become taller and more complex, establishing clear evacuation routes becomes very important in the event of a fire or other emergency. In this paper, Wireless Sensor Networks (WSN), Radio Frequency Identification (RFID) and real time escape route guidance are integrated to accomplish a real-time fire evacuation system to guide along an evacuation route. When the emergency event occurs, the system provides evacuation route guidance to people for them to be able to avoid danger. Moreover, in the proposed system, an intelligent evacuation route is provided by indicating in digital signage the best evacuation route as well as pertinent information to improve the chances of survival for users. The proposed system also supplies real time environmental information to fire fighters assuring better efficiency in their rescue operations.