Under the axial load of human weight on the femoral articular cartilage with 40% removal of meniscus high contact stresses took place on cartilage surface. Further, with 30%, 40%, 50% of meniscectomy significant amount of contact area noticed between femoral and tibial articular cartilage. After 65% of meniscectomy the maximal shear stress in the cartilage increased up to 225% compared to knee with intact meniscus. It appears that meniscectomies greater than 20% drastically increases the stresses in the knee joint.