Pulmonary hypertension is a well-known complication of systemic sclerosis. Patients with systemic sclerosis may develop a pulmonary arteriopathy characterized by vascular remodeling, increased pulmonary vascular resistance, and right ventricular failure. Pulmonary hypertension may also arise in systemic sclerosis as a consequence of interstitial lung disease or left ventricular dysfunction. Vascular remodeling is more prevalent than other forms of pulmonary hypertension in systemic sclerosis. The pathogenesis of pulmonary vascular remodeling in this disease state is not completely understood; however, there is evidence of a complex process involving genetic susceptibility, risk factors, vascular injury, and endothelial dysfunction. In those patients with pulmonary arterial hypertension, survival prognosis is extremely poor if the diagnosis is delayed or goes undetected and untreated. In recent years, a number of disease-targeted therapies have been developed that improve functional capacity, hemodynamics, and survival. Early detection and treatment with one or more targeted therapies are essential to improving survival when systemic sclerosis is complicated by pulmonary arterial hypertension.

The medical field has been emerged in the various sectors but the current blood glucose monitoring (BGM) are invasive as they require a finger prick blood sample, a repetitively painful process that creates the risk of infection. Hundreds of millions of dollars have been invested in companies who have sought the solution to this long-standing problem. Approaches that have been tried include near infrared spectroscopy (measuring glucose through the skin using light of slightly longer wavelengths than the visible region), measuring the amount that polarized light is rotated by glucose in the front chamber of the eye (containing the "aqueous humor"),and many others. This device provide a solution by interfacing a electronic device that has the capability of monitoring the glucose level, heart rate and temperature using non-invasive method which has less risk factors. This is a continuous monitoring device. So it helps to prevent the organ losses due to the low and high level of glucose, heart rate, temperature.