Background: This present studies intended to evaluate the wound healing ability, efficacy and tolerability of lysine cream (15%) in non- diabetic foot ulcer assessed by way of sessing scale.Methods: A randomized, open-label, interventional study was directed on 20 subjects (participants) non-diabetic ulcers. Participants were grouped into two groups, control (n=10) and case (n=10). The control was treated with standard treatment with mupirocin and the test group was treated with standard treatment alongside lysine cream (15%) twice every day. Wound healing in the participants was assessed by the sessing scales.Results: A total of 20 participants were allotted into two groups. The results expressed as mean±standard deviation values imply the size and depth of the foot ulcer from the first week to the 8th week. Both the groups showed a significant increase the ulcer healing and decrease the pressure of foot ulcer of over a period of 8 weeks. Assessment of the first week showed no significant ulcer healing and its pressure. The overall outcome indicated that the lysine-treated group extensively reduced each of the parameters favouring wound healing than the standard therapy with mupirocin (control group).Conclusions: Results concluded that, lysine cream is better efficacious in the repair of wound and additionally well tolerated compared to mupirocin.

Introduction: Hysterectomy is a reasonably safe, common and routine surgical procedure which rarely leads to perioperative death. Minor complications include postoperative infections, fever, wound hematomas or wound separation occur in approximately 25% of patients.Objective: A comparative assessment of the post-operative outcomes of Sri Lankan patients subjected to total abdominal hysterectomy and ascending vaginal hysterectomy for benign uterine diseases.Methods: A randomized controlled trial was conducted on 60 patients who underwent hysterectomy from July 2013 to June 2014, in a tertiary care hospital. Women those who were waiting for hysterectomy for benign uterine diseases within age 35-55yrs were included for the study. 30 patients underwent abdominal hysterectomy and 30 patients underwent vaginal hysterectomy. Five main variables were measured such as operative time in minutes, blood loss, post operative pain, pyrexia, hospital stay in days. Data entered and analyzed by SPSS 25.0.Result: Age of participants was between 37 to 51 years of age. Mean age was 44.87 years among vaginal hysterectomy group (SD 3.4 years) and 44.71 among abdominal hysterectomy group (SD 3.756 years).The average time duration for two procedures (t=10.4: p<0.05), average post operative hospital stay (t-10.1 ; df-58 ; p<0.05), onset of post operative pain (X 2 -31.0: df -2: p<0.05) and average blood losses between two groups (t-14.97; df-58; p<.05) were significantly different. Onset of fever was not significantly different in two groups (X 2 -0.48:df-1: p=.731). Conclusion:When comparing abdominal hysterectomy and vaginal hysterectomy the time taken for abdominal hysterectomy and post operative stay at hospital following abdominal hysterectomy is higher than those of vaginal hysterectomy. Abdominal hysterectomy was associated with a significantly higher post operative pain.Onset of fever following surgery does not depend on the type of surgery.

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