The anterior guide is a functional entity, which is part of the set of guidance provided by the dento-dental joints to the mandibular kinematics, essential for the establishment of harmonious occlusal relations. The anterior guide is a key to understanding and reconstructing the occlusion, playing both a role of protecting the posterior teeth and guiding the functional movements of the mandible. Currently, it also represents an “exteroceptive feeler” creating a cone of access to the occlusion in intercuspation. The restoration of functional and protective anterior guidance is therefore essential for the balance of the masticatory system. This rehabilitation can only be achieved by examining and accurately diagnosing the occlusion relationships maintained by the anterior teeth, associated with a reasoned therapeutic approach validated by a test phase. After a brief description of the anterior function and its role, this article aims to detail, through a clinical case, the procedure to follow for the restoration of a functional anterior guide.

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Introduction. Management of missing maxillary lateral incisors can be a challenging endeavour for dentists. Whether from agenesis or tooth loss, several treatment modalities are currently present to tackle this task to ensure satisfactory aesthetics. Most patients, especially younger patients are more likely to prefer fixed prosthodontic rehabilitation. Among these options is the computer-aided design and computer-aided manufacturing polymethyl methacrylate (CAD/CAM PMMA) cantilever bridge. Case Descriptions. These two clinical cases describe the management of missing lateral maxillary incisors in two Tunisian female patients with different etiologies, using CAD/CAM PMMA cantilever bridge. Conclusions. CAD/CAM technologies allow for a fairly quick and simple try-in thanks to their high accuracy as well as being predictable, minimally invasive, and affordable treatment options. This type of restoration can be put to use for mid- to long-term solutions to missing maxillary lateral incisors. However, its success depends mainly on patient selection regarding age, general health, occlusal context, and proper indication.