Objective: To determine the frequency of hyperuricemia and fetal outcome in pre-eclamptic pregnant patients. Study Design: Cross-Sectional Study. Setting: Department of OBG Allied Hospital Faisalabad. Period: January 15, 2022 to January 15, 2023. Material & Methods: Total 200 preeclamptic patients were enrolled and 5c.c of blood was drawn for serum uric acid level. The normal values took 3.1-6.3 mg/dl. Fetal outcome were intrauterine death, premaurity, intrauterine growth restriction with low birth weight recorded. Results: Frequency of hyperuricemia was calculated as 42% (n=84) where normal uric acid levels were recorded in 58% (n=116). IUD in hyperuricemia was 8.33%(n=7) and 2.59%(n=3) in normal uric acid levels, p=0.06, preterm delivery in hyperuricemia was 52.38%(n=44) and 20.69%(n=24) in normal uric acid level, p=0.000, CS in 55.95%(n=47) in hyperuricemia and 22.41%(n=26) in normal uric acid levels whereas SVD was 44.05%(n=37) in hyperuricemia and 77.59%(n=90) in normal uric acid levels, p=0.000, low birth weight was recorded in 52.38%(n=44) in hyperuricemia whereas 14.66%(n=17) in normal uric acid levels, p=0.000. Conclusion: the frequency of fetal outcome is adverse in hyperuricemia in pre-eclamptic patients as compared to normal serum uric acid levels.
Grandmultiparity has long been classified as constituting a high risk factor in pregnancy. The complications associatedwith grandmultiparity have been divided into ante-partum, intra-partum and the postpartum. Intrapartum complications most commonlythought to be associated with grandmultiparity are malpresentations, placental disorders, postpartum hemorrhage and uterine rupture.Concerted effort should be instituted for effective family planning initiatives and specialized antepartum and intrapartum management.Objective: To determine the frequency of intrapartum complications and mode of delivery in grandmultipara. Material and Methods: Itis descriptive case series study conducted in department of obstetrics and gynaecology, Punjab Medical College and affiliated hospitals,Faisalabad from March 11, 2010 to September 10, 2010. Results: Grandmultipara women who fulfilled the inclusion criteria werestudied for intrapartum complications and mode of deliveries. One hundred and thirty nine patients were included in my study. Mean ageof the patients was 32.38 years. Mean gestational age for delivery was 37.06 weeks. Grandmultiparas had more intrapartumcomplications including malpresentation (19.4%), placental abruption (5.8%), placenta previa (8.6%), postpartum hemorrhage (6.5%)and ruptured uterus (1.4%). Mode of delivery was also assessed and 59%, 7.9 %, 31.7% of patients had normal vaginal delivery,instrumental vaginal delivery and cesarean section respectively. Conclusions: It is concluded that in the developing countries theincidence of grandmultiparity is still high with a significantly increased risk of complications. Grandmultiparity should be considered highrisk and needs active intervention by improving literacy, health care facilities, provision of safe and effective contraception andreproductive health status.
Objective: To determine the Accuracy of GCT for screening of gestational diabetes in high risk population comparing oralGlucose Tolerance Test (GTT) as gold standard. Main outcome measures: Accuracy of GCT. Study design: Cross-sectional study.Setting: The study was conducted in outpatient department of Punjab Medical College and affiliated hospitals, Faisalabad. Subjects: 207patients. Methods: High risk women from outpatient department were recruited on the basis of inclusion and exclusion criteria afterexplaining pros and cons of procedure. These women were subjected to GCT & GTT. GTT was taken as gold standard test and results ofGCT were compared with it. Main outcome measures recorded and results obtained. Results: Out of 207 women, GCT truly diagnosed 24women as having diabetes (true positive) & 175 women were found to have normal glucose metabolism (true negative). GCT failed todiagnose 5 diabetic women (false negative) & wrongly diagnosed 3 normal women as diabetics (false positive) against gold standardGTT. So GCT has diagnosed Gestational diabetes mellitus with the sensitivity of 82.7%, specificity of 98.3%, positive predictive value of88.8%, and negative predictive value of 97.2% and accuracy of 96.1%. Conclusions: GCT is a simple, easy, convenient and sensitive testthat has no limitation for time or prior fasting for gestational diabetes screening.
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