Although the electronic properties of conducting films have been widely explored in optoelectronic fields, the optical absorption abilities of surface-coated films for photothermal conversion have been relatively less explored in the production of antibacterial coatings. Here, we present catechol-conjugated poly(vinylpyrrolidone) sulfobetaine (PVPS) and polyaniline (PANI) tightly linked by ionic interaction (PVPS:PANI) as a novel photothermal antibacterial agent for surface coating, which can absorb broadband near-infrared (NIR) light. Taking advantage of the NIR light absorption, this coating film can release eminent photothermal heat for the rapid killing of surface bacteria. The NIR light triggers a sharp rise in photothermal heat, providing the rapid and effective killing of 99.9% of the Gram-positive and -negative bacteria tested within 3 min of NIR light exposure when used at the concentration of 1 mg/mL. Although considerable progress has been made in the design of antibacterial coatings, the user control of NIR-irradiated rapid photothermal destruction of surface bacteria holds increasing attention beyond the traditional boundaries of typical antibacterial surfaces.

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The development of cooperative drug delivery systems that can detect and target the disease site, with rapid trigger controlled drug release (internally and externally), is widely expected to change the landscape of future drug carriers. In this study a drug delivery system was developed for the cancertargeted release of chemotherapeutic agents inside living cells. This system is an environment sensitive (pH), and external photothermally remote controlled, cooperative image-guided drug delivery matrix. Partially carbonized fluorescence hyaluronic acid (HA-FCN) was conjugated with boronic acid (BA) to promote the formation of boronate ester with diol groups of b-cyclodextrin (CD) [HA-FCN-CD]. The pH influence mediated release of paclitaxel (PTX) from the CD cavity of HA-FCN-CD was utilized for targeted cancer bioimaging. This active-target delivery system (HA-FCN-CD-PTX) was found to show optical absorption properties similar to those of the near infrared (NIR) light sensitive carbonized material.This system exploits acidity for triggered drug release and rapid generation of mild photothermal heat to trigger burst release of PTX. Cooperative guided bioimaging that employs both internal pH responsive and external NIR controlled drug carriers is a promising method for chemotherapeutic release that can be adjusted according to physiological needs.