Almost half of our cohort was sarcopenic. Most of these patients are normal or overweight and would not be identified as malnourished by traditional measures. Sarcopenia was a predictor of surgery in patients with a body mass index ≥ 25. Identification of sarcopenia has implications for medical nutrition therapy as typically efforts are focused on underweight patients.
The findings indicate that platelet-associated P-selectin contributes to the recruitment of leukocytes and platelets in venules of hypercholesterolemic mice and that the P-selectin-mediated adhesive interactions also contribute to the impaired arteriolar function induced by hypercholesterolemia.
Objectives-T-lymphocytes and interferon-␥ (IFN-␥) contribute to leukocyte recruitment in postcapillary venules during hypercholesterolemia. Our objectives were to determine whether: (1) T-lymphocytes are the source of this IFN-␥, and (2) whether T-cell-derived IFN-␥ also mediates the accompanying arteriolar dysfunction and platelet adhesion.
Methods and Results
Some 4-aminoquinolines have a high activity in the treatment of bronchial asthma13-0 and malaria, as well as having antiarrhythmic23-0 properties. Compound
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