Our meta-analysis suggests that MI and ELA are equally effective treating Sanders type II and III fractures. However, MI is effective in improving the AOFAS score (Sanders type II); reducing the rate of wound complications; and shortening the time to surgery, duration of surgery and length of hospital stay.
Summary
Background
The biological mechanisms underlying the use of platelet‐rich plasma (PRP), as well as the efficacy and possible adverse effects of PRP, have not yet been fully elucidated. Prior studies have evaluated PRP for cutaneous ulceration. However, the benefits from PRP still remain controversial and few have assessed the effects of ulceration etiologies. The purpose of our study is to determine the efficacy and safety of PRP and which kind of ulcer is more suitable for PRP by analyzing the effects of PRP on ulcers with different causes.
Methods
A comprehensive search was performed to identify randomized controlled trials (RCTs) regarding the application of PRP from PubMed, EMBASE, Scopus, and the Cochrane Library. The data were analyzed using Review Manager 5.3.
Results
A total of nineteen RCTs (909 patients) were included. In contrast with conventional treatments, PRP achieved higher healing rate, higher percentage of area reduction, and smaller final area in vascular ulcers. However, the advantage disappeared in diabetic and pressure ulcers. Concerning adverse events, PRP showed lower incidence in the short term, but higher in the long term. No significant differences were found in ulcer closure velocity and healing time.
Conclusion
Platelet‐rich plasma effectiveness and safety in treating cutaneous ulceration depend on what is the ulceration etiology. For diabetic ulcers, PRP showed no satisfactory results suggesting that PRP may not be suitable for diabetic patients. However, PRP could be efficient and more beneficial for vascular ulcers and effects on pressure ulcers remain unclear. Thus, PRP option should be carefully considered for each patient in accordance with their ulceration etiologies.
Objective: To investigate the effect of percutaneous acupoint electrical stimulation combined with early lower limb massage on knee rehabilitation after reconstruction of anterior cruciate ligament injury. Methods: 120 cases of patients admitted to our hospital from January 2019 to December 2022 were selected as the study subjects, and all patients were divided into observation group and control group, with 60 patients in each group. The patients in the control group took routine postoperative rehabilitation treatment. The observation group added percutaneous acupoint electrical stimulation combined with early lower limb massage on the basis of the pain and swelling before and for 6 months in the two groups, location perception and motion perception and knee function in the two groups. Results: The swelling value and visual analog scale (VAS) scores in the two treatment groups were significantly decreased, and the observation group was lower than the control group (P <0.05); the knee and 45 degrees, knee extension and knee motion were lower than the control group (P <0.05); the knee subjective (IKDC) score and knee function (Lysholm) scores were significantly lower, and the observation group was lower than the control group (P <0.05). Conclusion: Percutaneous acupoint electrical stimulation combined with early lower limb massage can reduce the long-term pain and swelling after knee anterior cruciate ligament injury reconstruction, improve the patient's knee position and motion perception, and further improve the knee function and motor function.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.