Introduction: Recall and understanding of basic science knowledge is considered background for studying the clinical sciences but does not directly affect clinical knowledge. Our aim was to evaluate the basic medical sciences recall and explore the association between the knowledge of basic and clinical sciences concepts. Methods: The current descriptive study was conducted during the academic year 2009-10. It included 183 medical students (48.6% male, 51.4% female) from among 2 nd , 3 rd, 4 th and 5 th year students of Taibah University College of Medicine in AL-Madinah AL-Munawarah, Kingdom of Saudi Arabia. Response rate was 73%. We administered an anonymous knowledge test with 15 basic and clinical pairs of questions. Results: There was a statistical significant overall effect of the study year when the second basic year students score compared with the clinical year's scores for basic questions (6.4 ±1.9 and 5.68 ±1.7, F = 12.51, p<0.001) and for clinical questions (4.0 ± 2.5 and 4.5 ± 1.8, F = 14.73, p<0.001) respectively. Conclusions: We would recommend modification of basic knowledge education to correlate with clinical training such that the student would be able to assimilate concepts of disease at an integrative level.

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Background Nephrotic syndrome is one of the most common chronic kidney diseases in children. Steroid sensitive type constitutes about 90% and steroid resistant 10% of total cases.  Objectives These national adapted guidelines aim to frame evidence-based recommendations adopted or adapted from IPNA 2020, KDIGO 2021, and Japanese 2014 for diagnosis, evaluation, management and follow-up of nephrotic children for Steroid sensitive nephrotic syndrome (SSNS) as paper one to be followed with SRNS as paper two. Methodology Formulation of key questions was followed with review of literature, guided by our retrieved and appraised guidelines using Agree plus appraisal tool. After virtual monthly meetings through the year 2021, the final draft was validated considering the comments of external local reviewers and KDIGO-assigned reviewers.  Discussion Rationale behind the selection of adopted statements and tailoring of others to suit our local facilities’ expertise and disease profile was discussed in the text with reasons. Conclusion The provided guidelines aim to optimize patient care and outcome and suggest research areas lacking validated research recommendations.

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