Introduction: Dermatoglyphics may be of clinical significance to segregate those individuals who are at an increased risk for the presence of an impacted tooth. Dermatoglyphics seems to be promising as a non-invasive diagnostic tool to forecast the presence/absence of an impacted tooth. Objective The study aimed to analyze the most common pattern of dermatoglyphics present in an individual with/without impacted tooth and find a dermatoglyphic marker if any. Methods A cross-sectional study comprising of 180 subjects (90 cases and 90 control) was conducted. Blue duplicating ink was applied on the fingertips using the rolling impression technique and recorded. Results In individuals predisposed to the presence of impacted teeth, there was an increase in the frequency of WHORL-PLAIN pattern in right hand ring finger (60%) and left hand little finger (33.3%) with a p-value of 0.028 and 0.009 respectively, and LOOP-ULNAR in the right hand middle finger (74.4%) with a p-value of 0.024. Forward stepwise binary logistic regression analysis showed the left hand little finger to be the most predictive for impaction. Conclusion Dermatoglyphics could serve as a non-invasive marker to forecast the presence/absence of an impacted tooth. Its utility lies in early diagnosis to curtail the surgical complications associated with symptomatic removal of an impacted tooth.