INTRODUCTIONIn order to reduce the risk of maternal or neonatal morbidity and mortality, labour is often induced. 1According to WHO global survey reports, 9.6% of cases out of 3 lakhs population were delivered by labor induction. 2Prostaglandins are widely used in clinical practice since 1960s for induction of labour but side-effects such as ABSTRACT Background: Induction of labour by use of prostaglandins improves the obstetric outcome in complicated cases such as prolonged deliveries. The aim of the present study was to compare the effect of prostaglandin E1 (PGE1) and prostaglandin E2 (PGE2) for prelabour ripening of unfavourable uterine cervix in nulliparous women, to study the effect of PGE1 and PGE2 on duration of labor and to evaluate the obstetrical and neonatal outcome of induction of labour using prostaglandins E1 and E2. Methods: This was a prospective study conducted on 50 nulliparous women with singleton pregnancy with gestational age ≥37 weeks during the period from

Background: The incidence of caesarean section has increased in the past few years in both developed and developing countries. The aim of the study is to analyse the factors responsible for caesarean section in a multigravida women with previous normal delivery. Methodology: This is an observational study involving 70 multiparous women with history of previous normal vaginal delivery during the period from September 2015 to September 2018 in the department of Obstetrics and Gynaecology of GCS Medical College and Research Centre, Ahmedabad. The various parameters analysed were presentation of foetus, weeks of gestation, elective v/s emergency caesarean section, indication of caesarean section. Results: In the study, majority of patients belong to age group of 28-32 years (47.14%) and were gravida 2 (75.71%). 48 out of 70 women were between 37 to 40 weeks. The most common indication of caesarean section is foetal distress followed by breech presentation in our study and most caesarean were performed in emergency. Conclusion:Caesarean sections are effective in reducing maternal and neonatal mortality only when done for obstetric or medical indications. Knowledge of the factors responsible for caesarean in multigravida with previous normal delivery may assist obstetrician in overall patient management which ultimately will reflect in better maternal and neonatal outcome necessary for psychological and social wellbeing.

Background: Iron deficiency anemia is the most common type of nutritional anemia in pregnancy. Oral iron is the first treatment of choice because of its safety, easy availability and low cost, but compliance is a major issue due to its gastrointestinal side effects. Injectable iron sucrose can be an alternative in treatment of anemia where compliance is an issue with oral iron. Objective: Present study was done to compare the safety and efficacy of oral iron with intravenous iron sucrose in cases of mild to moderate anemia in pregnancy. Methodology: This was a prospective, randomised, interventional, comparative study carried out at GCS Medical College, Hospital and Research centre, Ahmedabad. The sample size was 100 with 50 patients in each group of treatment (oral iron and I.V. iron sucrose). The study was carried out from September 2015 to August 2016. Patients with haemoglobin 7 to 10 g/dl gestational age 14 to 36 weeks were considered for the study. Patients were randomly divided into 2 groups, group 1 was given oral iron in the form of ferrous fumarate containing 100 mg elemental iron twice a day for 4 weeks, while patients in group 2 were given 3 doses of I.V iron sucrose 200mg in 100 ml 0.9% normal saline on alternate days. Patients were followed up at 4 and 6 weeks of treatment. Results: The rise in haemoglobin levels after 4 and 6 weeks of treatment was comparable in both the groups and showed no statistical significance. Whereas the rise in serum ferritin levels after 4 and 6 weeks of treatment was much higher in I.V iron sucrose group as compared to oral iron group and it was found to be statistically significant (P<0.0001). There were no significant side effects or allergic reactions in I.V iron sucrose group. Conclusion: Oral iron and I.V iron sucrose had similar effects on rise in haemoglobin levels but iron sucrose had more effect on serum ferritin levels, hence it replenishes iron stores better and it has lesser side effects compared to oral iron.