Primary carcinoma of vagina is a rare entity in gynaecological oncology 1 . Carcinoma of vagina in prolapsed uterus is extremely rare .A tumour should be considered as a primary vaginal cancer when the cervix is uninvolved .A 65 years old (para 6) menopausal lady presented with retention of urine , pervaginal bleeding ,pelvic pain and irreducible uterovaginal prolapse .On vaginal examination , a large fungating growth (5-6cm)occupying the middle part of anterior and right lateral wall of vagina was found . Physical examination including digital rectal examination showed no involvement of parametrium, urinary bladder or rectum .Inguinal lymphnodes were not palpable. Biopsy was taken from the fungating growth. Histopathology examination diagnosed the case as squamous cell carcinoma of vagina. Paps smear of cervix and X ray chest revealed no abnormalities. IVU showed bilateral hydroureter and hydronephrosis ,CT scan of abdomen revealed procidentia with no parametrium or lymph node involvement . The patient was staged as having a FIGO stage I vaginal carcinoma and TNM(T1N0M0)The treatment performed was radical vaginal hysterectomy and excision of the whole vagina .Histopathology confirmed the squamous cell carcinoma of vagina . All the resection margins of the surgical a.Dr Carcinoma of vagina is considered the rarest gynaecological neoplasms. It represents less than 1-2% of gynaecological malignancies. Its incidence peaks during 60s 1,2,3 . Among them 85% are squamous cell carcinoma.Few cases of vaginal carcinoma associated with uterine prolapse are reported [5][6][7][8] . Common factors that may
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