Objective To examine potential risk factors associated with the success rate following fallopian tube recanalization (FTR) in infertile women with obstruction of the proximal fallopian tube. Methods We retrospectively studied patients who underwent FTR for tubal obstructive infertility between January 2016 and December 2018 at the Third Affiliated Hospital of Guangzhou Medical University. FTR was performed using a catheter and guidewire system to clear tubal obstruction. Predictive factors potentially associated with the success rate were assessed by logistic regression. Results A total of 762 patients were included. Multivariable analysis showed that age (odds ratio [OR] = 2.38, 95% confidence interval [CI]: 1.24–4.58), infertility type (OR = 2.82, 95% CI: 1.36–6.21), history of ectopic pregnancy (OR = 7.87, 95% CI: 4.05–15.81), history of abdominal surgery (OR = 4.30, 95% CI: 2.22–8.60), history of artificial abortion curettage (OR = 4.08, 95% CI: 2.12–8.03), and duration of infertility (OR = 2.03, 95% CI: 1.06–3.85) were independently associated with postoperative tubal patency. Conclusions Our findings suggest that risk factors, such as age ≥35 years, secondary infertility, duration of infertility ≥5 years, and histories of ectopic pregnancy, abdominal surgery, and artificial abortion curettage, affect the success rate of FTR. These factors may also predict surgical success in treating tubal obstructive infertility.
Bacillus plays a unique role in Baijiu brewing, but its functions have not been fully explored. In this study, Aspergillus niger, Saccharomyces cerevisiae and Thermoactinospora rubra were used as chassis microorganisms in a fermentation system. Bacillus subtilis and Bacillus licheniformis, which are common in Maotai-flavoured Baijiu, were studied in the fermentation. Their metabolic differences and effects on the formation of Baijiu flavour in the process of stacking fermentation were analysed. The combined fermentation system of B. licheniformis showed the highest glucose metabolism, good flavour production, the greatest number of flavour compounds and the highest contents of important compounds, including ethanol (80.51%) and tetramethylpyrazine (0.35%). The maximum concentrations of glucan, maltotriose, maltose monohydrate and glucose were 349.64, 70.98, 64.34 and 51.31 mg g −1 , respectively. These results suggested that the metabolism of sugar and its derivatives was closely related to the overall flavour of the fermentation system.
Objective: To estimate the related factors of hysterectomy in patients with Placenta accreta spectrum (PAS) after uterine artery embolization (UAE), and try to evaluate the effectiveness and safety of UAE in patients with PAS.Methods: From January 2012 to July 2020, a retrospective analysis was performed in 85 patients undergoing TAE for PAS. Information regarding clinical data, angiography as well as embolization details, and clinical outcomes was obtained. Univariate and multivariate analyses were performed to determine the factors related to hysterectomy.Results: Bleeding greater than or equal to 500ml during the delivery(p = 0.037), the placenta type by MR or US(placenta increta vs placenta percreta, P = 0.01) and the type of ovarian artery(No vs Bilateral, P = 0.005; Unilateral vs Bilateral, P = 0.01) were independent risk factors of hysterectomy in PAS patients treated with UAE. The area under the curve (AUC) of the predictive model that incorporated the independent risk factors was 0.844. Abnormal collateral vessels communicating with uterine artery were observed on angiography in 24 patients (28.2%) with 31 abnormal collateral vessels. The major abnormal collateral vessel was the abnormal branches of the internal iliac artery(n = 13), followed by the inferior vesical artery (n = 11), internal pudendal artery(n = 3), obturator artery (n = 2), vaginal artery(n = 1) and the abnormal branches of the external iliac artery(n = 1).Conclusions: TAE is safe and effective for patients with PAS. Bleeding greater than or equal to 500ml during the delivery, the placenta type by MR or US and the type of ovarian artery were related to the hysterectomy. For patients with hypertrophic ovarian-uterine artery anastomosis and no fertility requirements, Ovarian artery embolization(OAE) could be a feasible choice.
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