Most caucasian patients with X-linked ichthyosis (XLI) reportedly display large genomic deletions involving the entire steroid sulphatase (STS) gene and flanking regions. In this study, we investigated the deletion patterns of the STS gene and flanking regions in 12 unrelated Japanese patients with XLI using the polymerase chain reaction method with 10 markers, including the 5' and 3' ends of the STS gene. Eleven of the 12 patients exhibited deletion of this entire gene, whereas the twelfth patient showed no evidence of deletion. In 10 of the 12 patients, the entire region from DXS1139 to DXF22S1 was deleted, the most common deletion pattern observed in caucasian patients, indicating that there are no racial or ethnic differences.

Cell ConceptA high-dielectric constant material have received increasing attention in view of an application to ULSI DRAMs for keeping a simple cell structure. We demonstrate a new technology with a planar-type single stacked structure utilizing a high-dielectric constant film of Bal -,SrXTi03 (BST). The fabricated memory cell ca acitor shows a low leakage current of 2x10-9Ncm under an applied voltage of 3.3V and a large capacitance of 32fF/um2, which means that the BST film is equivalently as thin as 1.3nm of Si02. 3

Monocular architecture is an attractive candidate for a consumer drive. A raw data density of 663Gbits/inch 2 was achieved using this architecture with a blue laser and a high NA objective lens.978-1-4244-3343-8/09/$25.00©2009 IEEE

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