Background: Post-partum haemorrhage condition is a serious condition after delivery. Objective: The purpose of the present study was to see the efficacy and safety of misoprostol for the prevention of post-partum haemorrhage. Methodology: This analytic cross-sectional study was carried out in the Department of Gynaecology and Obstetrics at Mymensingh Medical College Hospital (MMCH), Mymensingh, Bangladesh from January 2006 to June 2006 for a period of six months. Pregnant women who were admitted in MMCH during the above period and were expected to have vaginal delivery and women at term with singleton pregnancy were included as study population. Women were divided into 2 groups. Women were in the group A who were treated with misoprostol and women who were treated with oxytocin were in group B. Blood loss during delivery was estimated subjectively by the attending obstetrician. Results: A total number of 100 women were recruited for this study of which 50 women were in the group A and the rest of 50 women were in group B. In this study majority of the patients were belonged to age group 20 to 25 years in both the groups. In oxytocin group 2.0% have developed nausea, 4.0% patients have developed shivering. None have developed vomiting, diarrhoea, temperature. In misoprostol group 10.0% patients have developed nausea, 18.0% patients have developed shivering, 4.0% patients have developed rise of temperature, none have developed diarrhoea, vomiting. The differences were statistically significant. In this study 4.0% patients from oxytocin group and 2.0% patient from misoprostol group required blood transfusion. Conclusion: In conclusion less amount of blood loss is found in misoprostol group than oxytocin group. Journal of National Institute of Neurosciences Bangladesh, July 2021, Vol. 7, No. 2, pp. 152-155

Background: Misoprostol is very useful for induction of labour among the pregnant women. Objective: The purpose of the present study was to see the indication and complication of induction of labour by misoprostol among pregnancy women. Methodology: This single center clinical trial was carried out in the Department of Obstetrics and Gynaecology at a private hospital in Dhaka city, Bangladesh from September 2005 to February 2006 for a period of six months. Primi or second gravida patients with the gestational age between 37 weeks to 42 weeks in singleton pregnancy with cephalic presentation and not in labour were selected as study population. After proper selection of the cases, induction of labour was done by applying tablet misoprostol 50mcg in the posterior vaginal fornix. Complication of induction were recorded. Result: A total number of 60 patients were recruited for this study. 24 patients were between 23 to 26 years and 12 patients were between 27 to 30 years. Pre-eclampsia, pregnancy induced hypertension and intrauterine growth retardation were the most common indication of induction. In this study 31(51.7%) patients needed only 1 dose of Misoprostol and 24 (40.0%) patients needed 2 doses and only 5(8.3%) patients needed 3 doses of Misoprostal. In this study 11.67% patients experienced Nausea & vomiting and 3.33% patients developed hyperstimulation. Conclusion: In the conclusion, the use of misoprostol results in a shorter induction to delivery time and miserable adverse effects on the method of delivery. Journal of Current and Advance Medical Research 2020;7(2): 80-83

Background: Surgical management of vesico-vaginal fistula is very crucial regarding the outcomes among the women. Objectives: The purpose of the present study was to see the surgical outcomes of vesico-vaginal fistula. Methodology: This cross-sectional study was carried out from July 2013 to December 2013 for a period of 6 months in the National Fistula Centre in the Department of Obstetrics & Gynaecology at Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh. All patients who underwent surgical repair for iatrogenic VVF in National Fistula Centre of the department of Obstetrics and Gynaecology of Dhaka Medical College Hospital were included in this study. Patients who got themselves admitted to Obstetrics & Gynaecology department of DMCH with the complaints of fistula. An interview usually lasted for an hour. The entire selected patients were interviewed for detailed history. Thorough physical examination was done. The surgical outcomes were recorded among the women. Result: A total number of 51 cases of VVF were recruited for this study. The mean age was 46.02 (±SD 6.104) years. Regarding the causes of iatrogenic vesico-vaginal fistula most of the cases (88.2%) were abdominal hysterectomy. In 4(7.8%) patients lower segment caesarean section caused the situation. Vaginal hysterectomy was responsible for 3.9% (2/51) cases of iatrogenic VVF. In more than 90% cases (46/51) the surgical outcome was successful; while in 5 patients’ fistula recurred 5 to 7 days following surgery. They were treated by re-operation later on. Conclusion: In conclusion abdominal hysterectomy is the most common cause of iatrogenic vesico-vaginal fistula with a very good surgical outcomes. Journal of National Institute of Neurosciences Bangladesh, 2019;5(1): 29-32

Background: The clinical profiles and urinary albumin are very important for the prediction of preeclampsia among the pregnant women. Objective: The purpose of the present study was to assess the clinical and demographic profiles as well as the urinary albumin for the prediction of preeclampsia among the pregnant women. Methodology: This cohort study was conducted in the OPD of the Department of Obstetrics and Gynaecology at Rajshahi Medical College Hospital, Rajshahi, Bangladesh from January 2013 to December 2014 for a period of two (2) years. This study was carried on pregnant woman attending in outdoor department of Gynaecology, Rajshahi Medical College Hospital, Rajshahi, Bangladesh before 20th weeks of pregnancy who were healthy normotensive primigravidae with singleton pregnancy. The details demographic profiles, edema were collected from the study population. Urinary albumin was estimated before 20th weeks and after 28th weeks of pregnancy. Result: In the present study, 75 women were included; all were before 20th weeks of pregnancy without any complication or any risk factor for developing PE. Among the study group incidence of PE was 16%. The population are 24(32.0%) low, 31(41.3%) middle and 20(26.7%) high in socio economic conditions. Education level of study population was 45% completed primary education level, illiterate (27%) and secondary education (28%). Edema was absent in 1st visit, in 2nd visit 6(+), 6(++) present who developed PE, 18(+) present who did not develop PE. Edema was absent in 1st visit and (+) 6(50.0%) and (++) in 6(50.0%) present who developed PE in 2nd visit. Urine albumin in 1st visit nil in 6(50.0%), trace in 3(25.0%) and (+) in 3(25.0%) who developed PE. Conclusion: In conclusion housewife living in urban area in middle income socioeconomic condition are the most commonly presented with preeclampsia and urinary albumin is the most commonly detected in the pregnant women presented with preeclampsia Journal of Science Foundation 2018;16(2):54-59

Background: Maternal outcome is an important issue among the primigravida women presented with fetal head engagement. Objectives: The purpose of the present study was to observe the maternal outcome of among the primigravida women presented with fetal head engagement. Methodology: This descriptive cohort study was carried out in the Department of Gynecology and Obstetrics at Sir Salimullah Medical College and Mitford Hospital, Dhaka from June 2006 to December 2006 for a period of sic (6) months. Primaigravida women with 38 or more weeks of pregnancy having single foetus with cephalic presentation were selected as study population. Maternal outcome was measured in terms of incidence of post-partum hemorrhage, injury to the birth canal, wound infection and puerperal sepsis. Result: A total number of 1440 pregnant women were recruited for this study. Maximum number of patients was in the age group of 21 to 24 years which was 897(62.29%). Post partum hemorrhage (PPH) was reported in 7(2.67%) cases in engaged group and 17(1.44%) cases in non-engaged group. Birth canal injury was recorded in 4(1.53%) cases and 12(1.02%) cases in engaged and non-engaged group respectively. Wound infection was found in 8(3.05%) cases and 81(6.88%) cases in engaged and non-engaged group respectively. Regarding puerperal sepsis it was found in 3(1.15%) cases and 11(0.93%) cases in engaged and non-engaged group respectively Conclusion: In conclusion PPH, birth canal injury, wound infection and puerperal sepsis are commonly found in non-engaged group Journal of Science Foundation 2018;16(2):34-37