A sensitive and specific IgG4 enzyme-linked immunosorbent assay (ELISA) with urine samples has been reported. To confirm elimination of bancroftian filariasis, the ELISA was used in a study conducted in Yongjia County and Gaoan City, People's Republic of China, where filariasis elimination was declared, with 10,409 students 5-16 years of age. The antibody positive rates were 0.08% in Yongjia and 0.34% in Gaoan. All positive samples were re-examined and found to be negative. Our results show that this ELISA is practical and useful for confirmation of the elimination of filariasis. If similar results are obtained in different filariasis-endemic countries, this method may be useful in global filariasis elimination programs.

Path planning of lunar robots is the guarantee that lunar robots can complete tasks safely and accurately. Aiming at the shortest path and the least energy consumption, an adaptive potential field ant colony algorithm suitable for path planning of lunar robot is proposed to solve the problems of slow convergence speed and easy to fall into local optimum of ant colony algorithm. This algorithm combines the artificial potential field method with ant colony algorithm, introduces the inducement heuristic factor, and adjusts the state transition rule of the ant colony algorithm dynamically, so that the algorithm has higher global search ability and faster convergence speed. After getting the planned path, a dynamic obstacle avoidance strategy is designed according to the predictable and unpredictable obstacles. Especially a geometric method based on moving route is used to detect the unpredictable obstacles and realize the avoidance of dynamic obstacles. The experimental results show that the improved adaptive potential field ant colony algorithm has higher global search ability and faster convergence speed. The designed obstacle avoidance strategy can effectively judge whether there will be collision and take obstacle avoidance measures.

The SSL/TLS protocol is widely used in data encryption transmission. Aiming at the problem of detecting SSL/TLS-encrypted malicious traffic with small-scale and unbalanced training data, a deep-forest-based detection method called DF-IDS is proposed in this paper. According to the characteristics of SSL/TSL protocol, the network traffic was split into sessions according to the 5-tuple information. Each session was then transformed into a two-dimensional traffic image as the input of a deep-learning classifier. In order to avoid information loss and improve the detection efficiency, the multi-grained cascade forest (gcForest) framework was simplified with only cascade structure, which was named cascade forest (CaForest). By integrating random forest and extra trees in the CaForest framework, an end-to-end high-precision detector for small-scale and unbalanced SSL/TSL encrypted malicious traffic was realized. Compared with other deep-learning-based methods, the experimental results showed that the detection rate of DF-IDS was 6.87% to 29.5% higher than that of other methods on a small-scale and unbalanced dataset. The advantage of DF-IDS was more obvious in the multi-classification case.

Aiming at unknown or variant ransomware attack encrypted with SSL (Secure Sockets Layer)/ TLS (Transport Layer Security) protocol, a detection framework named TGAN-IDS (Transferred Generating Adversarial Network-Intrusion Detection System) based on dual generative adversarial networks is presented in this paper. In this framework, DCGAN (Deep Convolutional Generative Adversarial Network) is adopted to train a generator which has good performance to generate adversarial sample, and is transferred to the generator of TGAN. A pre-training model named PreD is built based on CNN (Convolutional Neural Network), which has good performance to do binary classification, and is transferred to the discriminator of TGAN. The generator and discriminator of TGAN play games in training process until the discriminator has a strong ability to detection unknown attack, and then it is output as an anomaly detector. In order to suppress the deterioration of normal sample detection ability during adversarial training of TGAN, a reconstruction loss function is introduced into the target function of TGAN. Experiments on a mixed dataset which is constructed by CICIDS2017 and other ransomware datasets show comparing with other deep learning network, such as AlexNet, ResNet and DenseNet etc., TGAN-IDS performs well in the indicators of detection accuracy, recall or F1-score etc. Also experiments on KDD99, SWaT and WADI datasets show that TGAN-IDS is suitable for other unencrypted unknown network attack detection.INDEX TERMS Ransomware, encrypted traffic, anomaly detection, GAN, transfer learning.

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