Compared with biological nanopores, solid-state nanopores (SSN) have advantages in chemical, mechanical, and thermal stability, pore size tunability and integration, and detect a broader range of targets. However, the current problems of low signal-to-noise ratio (SNR), inefficient preparation, and poor reproducibility of solid-state nanopores remain unsolved, limiting their application to replace biological nanopores as the main sensor devices. In this paper, we address the low SNR problems of solid-state nanopores, introduce the recent research done by researchers to improve the SNR of solidstate nanopores, make a breakdown into the existing resistive pulse detection field, and give an outlook on various sensing detection methods based on nanopores.