Uterine fibroids in pregnancy present with numerous complications. However, spontaneous rupture is a rare and potentially life-threatening event. We report a case of a 43-year-old multiparous woman who presented with hypovolemic shock secondary to a ruptured uterine fibroid 2 days after a spontaneous vaginal delivery. Emergency laparotomy confirmed massive intra-abdominal hemorrhage from the ruptured capsule of a 10-cm subserosal fibroid. A myomectomy was performed. Her postoperative recovery period was uneventful. This case is very rare, with fewer than 30 cases of hemoperitoneum secondary to rupture of fibroids having been reported in published works. It demonstrates how a benign and common condition, such as fibroids, can lead to an obstetric emergency that mimics a surgical abdomen requiring swift diagnosis and surgical intervention.
Objectives
To assess the role of the cerebro‐placental ratio (CPR) in predicting adverse fetal outcomes among women with sickle cell disease (SCD).
Methods
A prospective cohort study at Korle‐Bu Teaching Hospital, Accra, Ghana, between January and June 2016. Pregnant women with SCD at 34 gestational weeks or more underwent weekly fetal umbilical and middle cerebral artery Doppler assessment until delivery. Participants were categorized into two study arms based on CPR (<1.1 or ≥1.1). The primary outcome, a composite of adverse perinatal outcomes including intrauterine growth restriction, stillbirth, low birthweight, and neonatal intensive care unit admission, was compared between groups.
Results
Overall, 48 pregnant women with SCD were enrolled, and 5 had a fetus with CPR less than 1.1. Low CPR (<1.1) had a sensitivity and specificity of 29.4% and 100%, respectively, for predicting composite adverse perinatal outcomes. Sensitivity and specificity were, respectively, 100% and 93.5% for predicting stillbirth, and 40.2% and 97.4% for predicting low birthweight. Perinatal outcomes did not differ between the two major sickle cell genotypes (hemoglobin SS and hemoglobin SC).
Conclusions
Among women with SCD, CPR less than 1.1 was associated with adverse perinatal outcomes, particularly low birthweight and stillbirth.
Twin Reversed Arterial Perfusion (TRAP) sequence is a rare complication of twin gestation unique to monochorionic twins, reported to occur in about 1% of all monochorionic pregnancies. In this condition, an acardiac twin, with an absent or non-functioning heart, is perfused by its co-twin (referred to as the “pump” twin) via placental anastomoses. It is associated with a high mortality for the pump twin without intervention. We report two cases of TRAP sequence diagnosed prenatally by ultrasound at the Korle Bu Teaching Hospital. We describe how this rare anomaly can be diagnosed and managed successfully even in a low resource setting to yield good perinatal outcomes.
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