Background
Major advances in different cancer treatment modalities have been made, and people are now living longer with cancer. However, patients with cancer experience a range of physical and psychological symptoms during and beyond cancer treatment. New models of care are needed to combat this rising challenge. A growing body of evidence supports the effectiveness of eHealth interventions in the delivery of supportive care to people living with the complexities of chronic health conditions. However, reviews on the effects of eHealth interventions are scarce in the field of cancer-supportive care, particularly for interventions with the aim of empowering patients to manage cancer treatment–related symptoms. For this reason, this protocol has been developed to guide a systematic review and meta-analysis to assess the effectiveness of eHealth interventions for supporting patients with cancer in managing cancer-related symptoms.
Objective
This systematic review with meta-analysis is conducted with the aim of identifying eHealth-based self-management intervention studies for adult patients with cancer and evaluating the efficacy of eHealth-based self-management tools and platforms in order to synthesize the empirical evidence on self-management and patient activation through eHealth.
Methods
A systematic review with meta-analysis and methodological critique of randomized controlled trials is conducted following Cochrane Collaboration methods. Multiple data sources are used to identify all potential research sources for inclusion in the systematic review: (1) electronic databases such as MEDLINE, (2) forward reference searching, and (3) gray literature. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines for conducting the review were followed. The PICOS (Population, Interventions, Comparators, Outcomes, and Study Design) framework is used to identify relevant studies.
Results
The literature search yielded 10,202 publications. The title and abstract screening were completed in May 2022. Data will be summarized, and if possible, meta-analyses will be performed. It is expected to finalize this review by Winter 2023.
Conclusions
The results of this systematic review will provide the latest data on leveraging eHealth interventions and offering effective and sustainable eHealth care, both of which have the potential to improve quality and efficiency in cancer-related symptoms.
Trial Registration
PROSPERO 325582; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=325582
International Registered Report Identifier (IRRID)
DERR1-10.2196/38758
Cornelean cherry is a very perishable fruit that requires proper postharvest management to reduce losses. This study was aimed to increase the postharvest life and marketability of the product using postharvest calcium chloride treatments. The present study was conducted in a factorial experiment based on a completely randomized design with three replications. Factors included 3 immersion calcium chloride treatments (0, 60 and 80 mM), 4 storage times (0, 10, 20 and 30 days) and two cornelean cherry genotypes. Fruit samples were harvested at maturity (more than 90% of red skin) and immersion treatments were applied on them. During and after the experiment, different physicochemical traits of fruits were studied. The results showed that KKP2 genotype had lower mean firmness and sugar content and higher weight loss percentage than Hir genotype. The results showed that the two genotypes did not show significant differences in terms of pH and titratable acidity. Firmness, titratable acid, ascorbic acid, anthocyanin and phenol decreased over time. Among immersion treatments, the highest and lowest firmness, titratable acid and ascorbic acid belonged to 60 mM calcium and control (distilled water), respectively. The difference between 60 and 80 mM calcium chloride treatments was not significant. The lowest fruit weight loss was obtained in 80 mM calcium chloride treatment.
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